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DiscoveryProbe™ Angiogenesis Library
A unique collection of 18 small molecule compounds for angiogenesis research.

Catalog No.L1047
Size Price Stock Qty
100uL/well(10 mM solution)
$620.00
In stock
250uL/well(10 mM solution)
$1,120.00
In stock
5mg/well
$1,460.00
In stock

Tel: +1-832-696-8203

Email: [email protected]

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Sample solution is provided at 25 µL, 10mM.

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Featured Products of the Library

Catalog No. Product Name Summary Targets CAS Number Smiles
A3001 PCI-32765 (Ibrutinib) Bruton's tyrosine kinase (BTK) inhibitor BTK 936563-96-1 C=CC(=O)N1CCCC(C1)N2C3=C(C(=N2)C4=CC=C(C=C4)OC5=CC=CC=C5)C(=NC=N3)N
A3302 CGI-1746 Btk inhibitor BTK 910232-84-7 CC1=C(C=CC=C1NC(=O)C2=CC=C(C=C2)C(C)(C)C)C3=CN(C(=O)C(=N3)NC4=CC=C(C=C4)C(=O)N5CCOCC5)C
A4506 DMOG Competitive HIF-PH inhibitor, cell-permeable HIF 89464-63-1 COC(=O)CNC(=O)C(=O)OC
A8164 Cyclo (-RGDfK) Inhibitor of αvβ3 integrin Integrin 161552-03-0 C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCN=C(N)N)CCCCN)CC2=CC=CC=C2)CC(=O)O
A8233 DMXAA (Vadimezan) Tumnor vascular disrupting agent, apoptosis inducer VDA 117570-53-3 CC1=C(C2=C(C=C1)C(=O)C3=C(O2)C(=CC=C3)CC(=O)O)C
A8660 Cilengitide Integrin inhibitor for αvβ3 and αvβ5 Integrin 188968-51-6 CC(C)C1C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)N1C)CC2=CC=CC=C2)CC(=O)O)CCCN=C(N)N
B3708 RGD (Arg-Gly-Asp) Peptides Inhibits integrin binding to RGD motifs Integrin 99896-85-2 C(CC(C(=O)NCC(=O)NC(CC(=O)O)C(=O)O)N)CN=C(N)N
B6004 PX-478 2HCl HIF-1α inhibitor HIF 685898-44-6 ClCC[N+](C1=CC=C(C[[email protected]@](N)([H])C(O)=O)C=C1)([O-])CCCl.Cl.Cl
Download the Angiogenesis-Library - XLSX       Download the Angiogenesis-Library - SDF

Quality Control

Related Biological Data

PCI-32765
In the Burkitt lymphoma cell line Namalwa, the anti-IgM–induced phosphorylation of protein kinase B (PKB/AKT) and ERK were inhibited by PCI-32765 , whereas phosphorylation of the activating LYN/SYK substrate site Y551 of BTK was actually upregulated.

Review (University of Minnesota)

PCI-32765
Fura-2 loaded purified basophils were incubated with vehicle control (0.0005% DMSO) or 50 nM PCI-32765 for 10 minutes prior to the addition of 0.5 μg/ml anti-IgE antibody and the cytosolic calcium response monitored. The 350/380 excitation ratio is plotted for the average of two experiments.

Review (Thomas Jefferson University)

PCI-32765
Src expression in BMMs cultured with RANKL and M-CSF for 3 days in the presence of ibrutinib at indicated concentration.

Related Biological Data

DMXAA (Vadimezan)

Related Biological Data

DMXAA (Vadimezan)

Related Biological Data

DMXAA (Vadimezan)

Signaling Pathway

Histone Acetyltransferases Compare Products
BTK Compare Products
Integrin Compare Products

Advantages

  • Available in stock with overnight delivery and free shipping over $500
  • Cost-effective and competitive price to save your findings
  • Potent, selective and cell-permeable in inhibiting or activating target molecules
  • Diverse in chemical structure and route of administration (oral/i.m/i.v injection etc.)
  • Detailed files describing potency, selectivity and applications etc.
  • Supported by published data from top peer-reviewed journals
  • Guaranteed high quality with NMR and HPLC validation

Storage and Shipping Information

Form Pre-dissolved DMSO solutions Stability -20°C: 12 months
-80°C: 24 months
Packaging 96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode.
General tips For obtaining a higher solubility , please warm the tube at 37°C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

Compound Library Composition