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Raf

Raf is a family of three serine/threonine-specific protein kinases that are related to retroviral oncogenes.

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  1. LY3009120
    A8716 LY3009120
    Target: Raf
    Summary: pan-RAF and RAF dimer inhibitor
      insoluble in H2O; insoluble in EtOH; ≥4.25 mg/mL
  2. PLX7904
    B6177 PLX7904
    Summary: paradox-breaker RAF inhibitor, potent and selective
      Soluble in DMSO
  3. B-Raf inhibitor 1
    B1172 B-Raf inhibitor 1
    Summary: Potent and selective B-Raf inhibitor
      ≥47.9 mg/mL
  4. B-Raf inhibitor 1 dihydrochloride
    B1173 B-Raf inhibitor 1 dihydrochloride
    Summary: B-Raf inhibitor,potent and selective
      ≥53.9 mg/mL
  5. Dabrafenib (GSK2118436)
    B1407 Dabrafenib (GSK2118436)
     3 Citation
    Target: Raf
    Summary: Inhibitor of BRAF(V600) mutants
      ≥26 mg/mL
  6. LGX818
    B1174 LGX818
    Target: Raf
    Summary: RAF inhibitor,potent and selective
      insoluble in EtOH; insoluble in H2O; ≥13.38 mg/mL
  7. Vemurafenib (PLX4032, RG7204)
    A3004 Vemurafenib (PLX4032, RG7204)
     9 Citation
    Target: Raf
    Summary: BRAF kinase inhibitor
      ≥24.5 mg/mL
  8. Sorafenib
    A3009 Sorafenib
     2 Citation
    Target: Raf|VEGFR
    Summary: Raf kinases and tyrosine kinases inhibitor
      ≥23.25 mg/mL
  9. PLX-4720
    A3016 PLX-4720
     1 Citation
    Target: Raf
    Summary: BRAF kinase inhibitor
      ≥20.69 mg/mL
  10. BRAF inhibitor
    A3263 BRAF inhibitor
    Summary: Potent B-raf inhibitor
      Soluble in DMSO

Items 1-10 of 27

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