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HCV

B5822 TMC647055 Choline salt

Summary: inhibitor of the hepatitis C virus NS5B polymerase

insoluble in H2O; insoluble in EtOH; ≥72.8 mg/mL
B1114 T 705

Target: RNA Polymerases

Summary: Potent and selective RNA-dependent RNA polymerase inhibitor

≥2.9 mg/mL
A8189 PSI-6206
3 Citation

Target: HCV polymerase

Summary: Inhibitor of HCV RNA polymerase,potent and selective

≥13.1 mg/mL
A5618 Daclatasvir (BMS-790052)

Target: HCV Proteases

Summary: HCV NS5A inhibitor

≥36.6 mg/mL
A4032 VX-222 (VCH-222, Lomibuvir)

Target: HCV polymerase

Summary: NNI of HCV RNA polymerase

≥44.6 mg/mL
A4031 Telaprevir (VX-950)
1 Citation

Target: HCV NS3-4A protease

Summary: HCV NS3-4A protease inhibitor

≥32.95 mg/mL
A4024 Danoprevir (RG7227)

Target: HCV Proteases

Summary: HCV NS3/4A protease inhibitor

≥32.6 mg/mL
A3909 VCH-916

Summary: HCV NS5B polymerase inhibitor

Soluble in DMSO
A3864 Tegobuvir

Summary: HCV RNA replication inhibitor

≥24.95 mg/mL
A3820 Simeprevir
1 Citation

Target: HCV Proteases

Summary: Inhibitor of HCV NS3/4A protease

insoluble in H2O; insoluble in EtOH; ≥18.75 mg/mL