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ADC Linker

C6575 H-Val-Ala-OH

Insoluble in DMSO; insoluble in EtOH; ≥14.35 mg/mL
BA2711 Val-Ala-PABC-Exatecan

Summary: Val-Ala-PABC-Exatecan is a drug-linker coupling compound (Drug-LinkerConjugatesforADC) consisting of cleavable Tesirinelinker and Exatecan (inhibitor, HY-13631).
BA2708 Cyclooctyne-O-amido-PEG4-VC-PAB-Gly-Gly-NH-O-CO-Exatecan

Summary: Cyclooctyne-O-amido-PEG4-VC-PAB-Gly-Gly-NH-O-CO-Exatecan be used as a drug-linker coupler for ADC.
BA2705 Azido-PEG4-Val-Cit-PAB-MMAE

Summary: Azido-PEG4-Val-Cit-PAB-MMAE is part of an antibody coupled active molecule (drug-linkerconjugateforADC).
BA2685 MC-EVCit-PAB-MMAE

Summary: MC-EVCit-PAB-MMAE (Linker-Payload11) is an ADC (drug-linkerconjugates>.
BA2680 Ac-Lys-Val-Cit-PABC-MMAE

Summary: Ac-Lys-Val-Cit-PABC-MMAE is part of the antibody-coupled active molecule.
BA2676 Val-Ala-PAB-MMAE

Summary: Val-Ala-PAB-MMAE is a Drug-LinkerConjugatesforADC.
BA2651 MC-SN38

Summary: MC-SN38 is an active molecular coupler consisting of SN38, a potent microtubule disruptor, and a non-cleavable MClinker for the synthesis of antibody active molecular couplers (ADCs).
BA2643 DM21

Summary: DM21 is a cleavable affix of an ADC active molecule and linker (ADClinker).
BA2628 SMCC-DM1

Summary: SMCC-DM1 (DM1-SMCC) is formed by linking the linkerSMCC to the toxic molecule DM1 and can be used to prepare antibody-coupled active molecules.