Protein Tyrosine Kinase/RTK
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C9130 SelitrectinibSummary: A selective TRK inhibitor, suitable for in vitro kinase signaling research, for research use only. -
C9100 Tirabrutinib HClSummary: A selective irreversible BTK inhibitor for research in immunology and tumor biology.
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C9072 DesMethyl Erlotinib HClSummary: An EGFR inhibitor compatible with CuAAC labeling, for in vitro research use.
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C8982 Pirtobrutinib (LOXO-305)Summary: Pirtobrutinib (LOXO-305) is a highly selective, non-covalent Bruton's tyrosine kinase inhibitor targeting B-cell receptor signaling, widely utilized in hematologic malignancy research.
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C8979 Pralsetinib (BLU-667)Summary: Pralsetinib (BLU-667; CAS 2097132-94-8) is a selective RET tyrosine kinase inhibitor targeting RET signaling, widely utilized in oncology and molecular signaling research.
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C8976 Avapritinib (BLU-285)Summary: Avapritinib (BLU-285; CAS 1703793-34-3) is a selective KIT and PDGFRA tyrosine kinase inhibitor widely utilized in oncology and signal transduction research.
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C8921 Ripretinib (DCC-2618)Summary: Ripretinib (DCC-2618; CAS 1442472-39-0) is a switch-control tyrosine kinase inhibitor targeting KIT and PDGFRA, widely used in oncology and kinase-signaling research.
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C8918 Ritlecitinib (PF-06651600)Summary: Ritlecitinib (PF-06651600; CAS 1792180-81-4) is a selective covalent JAK3/TEC family kinase inhibitor used to investigate cytokine signaling and immune-cell pathway biology.
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C8917 TucatinibSummary: Tucatinib is a selective small-molecule HER2 tyrosine kinase inhibitor targeting ERBB2 signaling, widely utilized as a chemical probe in oncology and signal transduction research.
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C8914 FursultiamineSummary: Fursultiamine is a lipophilic thiamine derivative used to investigate vitamin B1 metabolism, thiamine-dependent enzymatic pathways, and cellular bioenergetics in biochemical research.