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MDM2

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  1. SP 141
    C4120 SP 141
    Summary: Mdm2 inhibitor
      ≤100 mg/mL
  2. (±)-Nutlin-3
    B6058 (±)-Nutlin-3
    Summary: MDM2 antagonist, potent and selective
      ≥50.1 mg/mL
  3. MI-77301 (SAR405838)
    B4984 MI-77301 (SAR405838)
    Summary: orally available MDM2 antagonist
      ≥17.2 mg/mL
  4. Pifithrin-β
    B4813 Pifithrin-β
    Summary: potent p53 inhibitor
      Soluble in DMSO
  5. YH239-EE
    B4756 YH239-EE
    Summary: p53-MDM2 antagonist, potent
      ≥50.4 mg/mL
  6. p53/MDM2 Set I
    A9903 p53/MDM2 Set I
    Summary: For inhibiting MDM2-p53 interaction
  7. NSC 66811
    A4230 NSC 66811
    Summary: MDM2 inhibitor
      ≥34 mg/mL
  8. NSC 207895 (XI-006)
    A4209 NSC 207895 (XI-006)
    Target: MDMX
    Summary: MDMX inhibitor,anti-cancer agent
  9. JNJ-26854165 (Serdemetan)
    A4204 JNJ-26854165 (Serdemetan)
     1 Citation
    Target: p53|HDM2 ubiquitin ligase
    Summary: P53 activator, blocking Mdm2-p53 interaction
      insoluble in EtOH; insoluble in H2O; ≥14.8 mg/mL
  10. RITA (NSC 652287)
    A4202 RITA (NSC 652287)
    Summary: Mdm2-p53 interaction and p53 ubiquitination blocking
      insoluble in H2O; ≥14.6 mg/mL

Items 1-10 of 13

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