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EGFR

B6115 RG 13022

Summary: EGFR tyrosine kinase inhibitor

≥26.6 mg/mL
B5962 AZD3759

Summary: EGFR inhibitor，oral active

≥23 mg/mL
B5836 AZ5104

Target: EGFR

Summary: EGFR inhibitor

insoluble in H2O; ≥16.95 mg/mL
B1496 Icotinib

Summary: EGFR tyrosine kinase inhibitor

insoluble in H2O; ≥129.6 mg/mL
B1495 OSI-420 free base

Summary: EGFR inhibitor

insoluble in H2O; insoluble in EtOH; ≥51 mg/mL
B1105 AZD-9291 mesylate

Summary: third generation EGFRm inhibitor, oral and irreversible

insoluble in EtOH; insoluble in DMSO; insoluble in H2O
B1104 AZD-9291
1 Citation

Target: EGFR

Summary: Mutated forms EGFR inhibitor

≥24.98 mg/mL
B1103 Mutant EGFR inhibitor

Summary: Selective Mutated EGFR inhibitor

Soluble in DMSO
B1020 AST-1306 TsOH

Summary: ErbB2 and EGFR inhibitor

Soluble in DMSO
A8375 AZD8931 (Sapitinib)

Target: EGFR|ErbB

Summary: ErbB inhibitor

≥23.7 mg/mL