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ALK

C4025 CEP-28122

Summary: anaplastic lymphoma kinase (ALK) inhibitor

≤30 mg/mL
B5859 Entrectinib

Target: Trk Receptors|ALK|ROS1

Summary: Orally active inhibitor of ALK kinase

≥28.05 mg/mL
B4882 PF-06463922

Target: ALK|ROS1

Summary: ALK/ROS1 inhibitor,potent and selective

insoluble in H2O; ≥20.3 mg/mL
B4842 LDN-214117

Summary: potent and selective ALK2 inhibitor

insoluble in H2O; ≥90 mg/mL
B3688 ML347

Target: BMP and Other Activin Receptors

Summary: BMP receptor inhibitor,potent and selective

insoluble in H2O; insoluble in EtOH; ≥5.87 mg/mL
B3687 LDN-212854

Summary: BMP receptor inhibitor,potent and selective

insoluble in H2O; insoluble in EtOH; ≥20.3 mg/mL
B3686 DMH-1

Target: BMP and Other Activin Receptors

Summary: Selective BMP ALK2 receptor

insoluble in H2O; insoluble in EtOH; ≥9.51 mg/mL
B3608 Crizotinib hydrochloride

Summary: inhibitor of the c-Met kinase and the NPM-ALK

≥100.4 mg/mL
A8620 AZD-3463
3 Citation

Target: ALK|Insulin-like growth factors (IGFs)

Summary: ALK/IGF1R inhibitor

insoluble in H2O; insoluble in EtOH; ≥11.22 mg/mL
A8440 GSK1838705A

Target: Insulin and Insulin-like Receptors|ALK

Summary: IGF-IR/IR/ALK inhibitor, ATP-competitive

≥26.65 mg/mL