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ALK

A8393 CH5424802

Target: ALK

Summary: ALK inhibitor,potent and ATP-competitive
A8328 LDK378

Target: ALK

Summary: Potent ALK inhibitor

insoluble in H2O; ≥13.95 mg/mL
A8324 LDN-193189
8 Citation

Target: BMP and Other Activin Receptors

Summary: ALK inhibitor,potent and selective

insoluble in DMSO; insoluble in EtOH; insoluble in H2O
A8251 TAE684 (NVP-TAE684)

Summary: ALK inhibitor,potent and selective

≥61.4 mg/mL
A5602 SB525334

Summary: (TGF-beta1) receptor inhibitor

≥34.3 mg/mL
A3545 LDN193189 Hydrochloride
1 Citation

Summary: ALK inhibitor,potent and selective

≥27.6 mg/mL
A3544 LDK378 dihydrochloride

Summary: ALK inhibitor
A3193 ASP3026

Summary: ALK inhibitor,potent and selective

insoluble in H2O; ≥14.53 mg/mL
A3155 ALK inhibitor 2

Summary: ALK inhibitor, novel and selective

Soluble in DMSO
A3020 (R)-Crizotinib
3 Citation

Target: c-MET

Summary: C-MET/ALK inhibitor,potent and ATP-competitve

insoluble in H2O; insoluble in EtOH; ≥7.51 mg/mL