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ADC Linker

Items 41-50 of 52

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  1. SPDP
    BA2378 SPDP
  2. DBCO-amine
    BA2367 DBCO-amine
    Summary: DBCO-amine is a degradable (cleavable) linker for the synthesis of antibody coupled active molecules (ADCs).
  3. MC-Val-Cit-PAB
    BA2366 MC-Val-Cit-PAB
    Summary: MC-Val-Cit-PAB is a synthesized intermediate and is a toxin-Linker coupling (Drug-Linker Conjugates for ADC).
  4. SMCC
    BA2364 SMCC
    Summary: SMCC is a protein cross-linking agent.
  5. DM4
    BA2323 DM4
    Summary: DM4 is an anti-microtubule protein agent that inhibits cell division.
  6. Mertansine
    BA2321 Mertansine
    Summary: Mertansine (DM1) is an inhibitor and an antibody-conjugatable medetomidine alkaloid used to overcome the systemic toxicity associated with medetomidine and to enhance tumor-specific delivery.
      ≥26.65 mg/mL
  7. Tubulysin
    BA1132 Tubulysin
    Summary: Secondary metabolites of the Tubulysin family were originally isolated from Mucor and
  8. Calicheamicin
    BA1006 Calicheamicin
    Summary: Calicheamicin is a tumor antibiotic and potent cytotoxic agent that causes DNA double-strand breaks.
  9. MMAF
    B3270 MMAF
    Target: Microtubules/Tubulins
    Summary: Anti-mitotic/anti-tubulin/antineoplastic agent
      ≥36.6 mg/mL
  10. Mc-Val-Cit-PABC-PNP
    B1003 Mc-Val-Cit-PABC-PNP
    Summary: Cathepsin cleavable ADC peptide linker
      ≥36.9 mg/mL

Items 41-50 of 52

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