Mc-Val-Cit-PABC-PNP

Catalog No.

B1003

Cathepsin cleavable ADC peptide linker

Grouped product items
Size	Price	Stock
10mg	$55.00	In stock
50mg	$143.00	In stock
100mg	$198.00	In stock

For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Background

Mc-Val-Cit-PABC-PNP is a cathepsin cleavable ADC peptide linker. For example, FDA approved drug, brentuximab vedotin, adopts this linker.

Physical Appearance	A solid
Storage	Store at -20°C
M.Wt	737.76
Cas No.	159857-81-5
Formula	C₃₅H₄₃N₇O₁₁
Solubility	≥36.9 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
Chemical Name	(Z)-6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-((S,Z)-1-hydroxy-1-(((S)-5-((hydroxy(imino)methyl)amino)-1-((4-((((4-nitrophenoxy)carbonyl)oxy)methyl)phenyl)amino)-1-oxopentan-2-yl)imino)-3-methylbutan-2-yl)hexanimidic acid
SDF	Download SDF
Canonical SMILES	CC([C@@](/N=C(O)/CCCCCN1C(C=CC1=O)=O)([H])/C(O)=N/[C@@](C(NC2=CC=C(COC(OC3=CC=C(N(=O)=O)C=C3)=O)C=C2)=O)([H])CCCNC(O)=N)C
Shipping Condition	Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips	We do not recommend long-term storage for the solution, please use it up soon.

Purity = 98.00%