Cell Counting Kit-8 (CCK-8)
Catalog No.
K1018
For cell proliferation and cytotoxicity assays.
Featured Products
Our Cell Counting Kit-8 (CCK-8) offers a more convenient and sensitive method for cell counting, cell proliferation, and cytotoxicity assays compared to previous methods. The kit utilizes WST-8, a highly water-soluble tetrazolium salt, which is reduced in the presence of an electron mediator to generate a water-soluble formazan dye. The amount of formazan produced by dehydrogenase activity is directly proportional to the number of living cells. CCK-8 exhibits superior sensitivity compared to alternative methods such as MTT, XTT, MTS, or WST-1 assays.
Figure 1. Principle of the CCK-8 detection
Figure 2. Cell number determination using CCK-8 reagent
- 1. Bin Cheng, Jie Zhou, et al. "Dual-responsive metal polyphenol network nanosheets for diabetic wound healing." Chemical Engineering Journal, 2024, p. 153071
- 2. Kai Wang, Xin Zhang, et al. "Reactivation of MAPK-SOX2 pathway confers ferroptosis sensitivity in KRAS." Redox Biol. 2024 Nov 5:78:103419.
- 3. Ting Li, Chengting Luo, et al. "Nicotinamide mononucleotide protects STAT1 from oxidative stress‐induced degradation to prevent colorectal tumorigenesis." MedComm (2020). 2024 Nov 21;5(12):e70006. PMID: 39575303
- 4. Yanyan Zhang, Yun Huang, et al. "Demethylzeylasteral induces PD-L1 ubiquitin–proteasome degradation and promotes antitumor immunity." Acta Pharm Sin B. 2024 Oct;14(10):4312-4328. PMID: 39525573
- 5. Ruipei Xiao, Wenli Zhao, et al. "Bendamustine–rituximab elicits dual tumoricidal and immunomodulatory responses via cGAS–STING activation in diffuse large B-cell lymphoma." J Immunother Cancer. 2024 Nov 9;12(11):e009212 PMID: 39521616
- 6. Jialin Chen, Renwang Sheng, et al. "Controlled TPCA-1 delivery engineers a pro-tenogenic niche to initiate tendon regeneration by targeting IKKβ/NF-κB signaling." Bioact Mater. 2024 Oct 23:44:319-338 PMID: 39512422
- 7. Mingru Bai, Ting Wang, et al. "Electron-donable heterojunctions with synergetic Ru-Cu pair sites for biocatalytic microenvironment modulations in inflammatory mandible defects." Nat Commun. 2024 Nov 6;15(1):9592 PMID: 39505847
- 8. Runzhi Liao, Marley J Dewey, et al. "Matrix-bound nanovesicles alleviate particulate-induced periprosthetic osteolysis." Sci Adv. 2024 Oct 18;10(42):eadn1852. PMID: 39423278
- 9. Yan Li, Zimu Zhang, et al. "Enhancer looping protein LDB1 modulates MYB expression in T-ALL cell lines in vitro by cooperating with master transcription factors." J Exp Clin Cancer Res. 2024 Oct 9;43(1):283 PMID: 39385230
- 10. Xin Pan, Lan Wang, et al. "TRβ activation confers AT2-to-AT1 cell differentiation and anti-fibrosis during lung repair via KLF2 and CEBPA." Nat Commun. 2024 Oct 7;15(1):8672. PMID: 39375377
- 11. Zhi Zhong, Xiu-Liang Cui, et al. "Apoptotic vesicles (apoVs) derived from fibroblast-converted hepatocyte-like cells effectively ameliorate liver fibrosis." J Nanobiotechnology. 2024 Sep 5;22(1):541 PMID: 39238002
- 12. Qian Song, Chengchen Hu, et al. "Integrated multi-omics approaches reveal the neurotoxicity of triclocarban in mouse brain." Environ Int. 2024 Sep:191:108987. PMID: 39217723
- 13. Luopin Wang, Aryamav Pattnaik, et al. "Unbiased discovery of cancer pathways and therapeutics using Pathway Ensemble Tool and Benchmark." Nat Commun. 2024 Aug 24;15(1):7288 PMID: 39179644
- 14. Zilin Zhou, Lizhong Sun, et al. "Exploring Naturally Tailored Bacterial Outer Membrane Vesicles for Selective Bacteriostatic Implant Coatings." Adv Sci (Weinh). 2024 Oct;11(39):e2405764 PMID: 39166390
- 15. Ji Qi, Long Zhang, et al. "Stepwise-targeting and hypoxia-responsive liposome AMVY@NPs carrying siYAP and verteporfin for glioblastoma therapy." J Nanobiotechnology. 2024 Aug 20;22(1):495 PMID: 39164753
- 16. Liang Cheng, Chenwei Yang, et al. "Oncogenic SLC2A11–MIF fusion protein interacts with polypyrimidine tract binding protein 1 to facilitate bladder cancer proliferation and metastasis by regulating mRNA stability." MedComm (2020). 2024 Aug 14;5(9):e685 PMID: 39156764
- 17. Junqi Shan, Xinyu Li, et al. "Palmitoyltransferase ZDHHC6 promotes colon tumorigenesis by targeting PPARγ-driven lipid biosynthesis via regulating lipidome metabolic reprogramming." J Exp Clin Cancer Res. 2024 Aug 16;43(1):227 PMID: 39148124
- 18. Zhaojie Wang, Yuxin Bai, et al. "Two-Way Regulation of MgFe-LDH on ESC Cell Fate via Temporal Selective Activation of Different Cell Membrane Receptors." ADVANCED FUNCTIONAL MATERIALS Volume34, Issue33 August 14, 2024 2314112
- 19. Yiliang Wang, Nu Li, et al. "Hemoglobin nanoclusters-mediated regulation of KPNA4 in hypoxic tumor microenvironment enhances photodynamic therapy in hepatocellular carcinoma." J Nanobiotechnology. 2024 Aug 9;22(1):473 PMID: 39135024
- 20. Xin Jin, Chengxiong Wei, et al. "Polyphenol-mediated hyaluronic acid/tannic acid hydrogel with short gelation time and high adhesion strength for accelerating wound healing." Carbohydr Polym. 2024 Oct 15:342:122372. PMID: 39048222
- 21. Tongting Ji, Yang Yang, et al. "Targeting RBM39 through indisulam induced mis-splicing of mRNA to exert anti-cancer effects in T-cell acute lymphoblastic leukemia." J Exp Clin Cancer Res. 2024 Jul 24;43(1):205 PMID: 39044280
- 22. Yan Yan, Xinhao Li, et al. "A mussel-inspired, antibacterial, antioxidant, injectable composite hydrogel for the sustain delivery of salvianolic acid B for the treatment of frozen shoulder." Bioact Mater. 2024 Jun 19:40:396-416. PMID: 39022185
- 23. Yang Chen, Yu Zhou, et al. "Harnessing lipid metabolism modulation for improved immunotherapy outcomes in lung adenocarcinoma." J Immunother Cancer. 2024 Jul 8;12(7):e008811 PMID: 38977328
- 24. Pengcheng Zhou, Xuanlong Du, et al. "Engineered extracellular vesicles for targeted reprogramming of cancer-associated fibroblasts to potentiate therapy of pancreatic cancer." Signal Transduct Target Ther. 2024 Jun 24;9(1):151. PMID: 38910148
- 25. Honglong Zhang, Jun Yan, et al. "Selenium restored mitophagic flux to alleviate cadmium-induced hepatotoxicity by inhibiting excessive GPER1-mediated mitophagy activation." J Hazard Mater. 2024 Aug 15:475:134855. PMID: 38880044
- 26. Da Huang, Pedro Norat, et al. "Consistent Intraocular Pressure Reduction by Solid Drug Nanoparticles in Fixed Combinations for Glaucoma Therapy." Adv Sci (Weinh). 2024 Jun 14:e2401648. PMID: 38874068
- 27. Jing Liu, Yijiang Bai, et al. "ABCC1 deficiency potentiated noise-induced hearing loss in mice by impairing cochlear antioxidant capacity." Redox Biol. 2024 Aug:74:103218. PMID: 38870779
- 28. Mengjia Lin, Xiaoyun Zheng, et al. "The RNF214-TEAD-YAP signaling axis promotes hepatocellular carcinoma progression via TEAD ubiquitylation." Nat Commun. 2024 Jun 11;15(1):4995 PMID: 38862474
- 29. Haixia Wang, Zheng Liu, et al. "Spatiotemporal release of non-nucleotide STING agonist and AKT inhibitor from implantable 3D-printed scaffold for amplified cancer immunotherapy." Biomaterials. 2024 May 28:311:122645. PMID: 38850717
- 30. Meng Wang, Wen-Wei Li, et al. "Genome mining of sulfonated lanthipeptides reveals unique cyclic peptide sulfotransferases." Acta Pharm Sin B. 2024 Jun;14(6):2773-2785 PMID: 38828142
- 31. Xuemin He, Siying Wen, et al. "Glucagon-like peptide-1 receptor agonists rescued diabetic vascular endothelial damage through suppression of aberrant STING signaling." Acta Pharm Sin B. 2024 Jun;14(6):2613-2630. PMID: 38828140
- 32. Diguang Wen, Hang Xiao, et al. "N6-methyladenosine-modified SENP1, identified by IGF2BP3, is a novel molecular marker in acute myeloid leukemia and aggravates progression by activating AKT signal via de-SUMOylating HDAC2." Mol Cancer. 2024 May 31;23(1):116 PMID: 38822351
- 33. Xiaodan Li, Yanming Zuo, et al. "Develop targeted protein drug carriers through a high‐throughput screening platform and rational design." Adv Healthc Mater. 2024 May 28:e2401793. PMID: 38804201
- 34. Niranjan Venkateswaran, Roy Garcia, et al. "Tryptophan fuels MYC-dependent liver tumorigenesis through indole 3-pyruvate synthesis." Nat Commun. 2024 May 20;15(1):4266. PMID: 38769298
- 35. Jianqing Peng, Qin Wang, et al. "Phospholipids of inhaled liposomes determine the in vivo fate and therapeutic effects of salvianolic acid B on idiopathic pulmonary fibrosis." J Control Release. 2024 Jul:371:1-15. PMID: 38761856
- 36. Dadi Jiang, Youming Guo, et al. "IRE1α determines ferroptosis sensitivity through regulation of glutathione synthesis." Nat Commun. 2024 May 15;15(1):4114. PMID: 38750057
- 37. Haiqin Tang, Wenlin Chu, et al. "Seeking Cells, Targeting Bacteria: A Cascade‐Targeting Bacteria‐Responsive Nanosystem for Combating Intracellular Bacterial Infections." Small. 2024 May 7:e2311967. PMID: 38712482
- 38. Yuzhen Li, Chun Li, et al. "Polymeric Micellar Nanoparticles for Effective CRISPR/Cas9 Genome Editing in Cancer." Biomaterials. 2024 Sep:309:122573. PMID: 38677222
- 39. Ruipeng Lu, Jingjing Hong, et al. "Loss of OVOL2 in Triple‐Negative Breast Cancer Promotes Fatty Acid Oxidation Fueling Stemness Characteristics." Adv Sci (Weinh). 2024 Apr 16:e2308945. PMID: 38627980
- 40. Lingzhi Li, Ting Xiang, et al. "Inhibition of ACSS2-mediated histone crotonylation alleviates kidney fibrosis via IL-1β-dependent macrophage activation and tubular cell senescence." Nat Commun. 2024 Apr 13;15(1):3200 PMID: 38615014
- 41. Bo Wang, Bingkun Zhou, et al. "Type III interferon inhibits bladder cancer progression by reprogramming macrophage-mediated phagocytosis and orchestrating effective immune responses." J Immunother Cancer. 2024 Apr 8;12(4):e007808 PMID: 38589249
- 42. Mingming Song, Jiameng Tian, et al. "Efficient Delivery of Lomitapide Using Hybrid Membrane‐Coated Tetrahedral DNA Nanostructures for Glioblastoma Therapy." Adv Mater. 2024 Jun;36(24):e2311760. PMID: 38569065
- 43. Na An, Xiaoyuan Yan, et al. "Human periodontal ligament stem cell sheets activated by graphene oxide quantum dots repair periodontal bone defects by promoting mitochondrial dynamics dependent osteogenic differentiation." J Nanobiotechnology. 2024 Mar 27;22(1):133. PMID: 38539195
- 44. Wenbing Wan, Yang Feng, et al. "Carbonized Cellulose Aerogel Derived from Waste Pomelo Peel for Rapid Hemostasis of Trauma‐Induced Bleeding." Adv Sci (Weinh). 2024 May;11(19):e2307409. PMID: 38477567
- 45. Hehe Xiong, Heng Zhang, et al. "Coassembly Nanomedicine Mediated by Intermolecular Interactions Between Methotrexate and Baricitinib for Improved Rheumatoid Arthritis Treatment." ACS Nano. 2024 Mar 19;18(11):8337-8349. PMID: 38437640
- 46. Sandro Matosevic, et al. "synNotch-programmed iPSC-derived NK cells usurp TIGIT and CD73 activities for glioblastoma therapy." Nat Commun. 2024 Mar 1;15(1):1909. PMID: 38429294
- 47. Yu Du, Yu Zhou, et al. "APE1 inhibition enhances ferroptotic cell death and contributes to hepatocellular carcinoma therapy." Cell Death Differ. 2024 Feb 28. PMID: 38418695
- 48. Shuang Qu, Chen Yang, et al. "Pan-viral propagation blockade by inhibiting host cell PNPT1." Int J Antimicrob Agents. 2024 Feb 25:107124. PMID: 38412930
- 49. Mutian Jia, Li Chai, et al. "S-nitrosothiol homeostasis maintained by ADH5 facilitates STING-dependent host defense against pathogens." Nat Commun. 2024 Feb 26;15(1):1750 PMID: 38409248
- 50. Yutong Wang, Yiming Huo, et al. "Engineered exosomes with enhanced stability and delivery efficiency for glioblastoma therapy." J Control Release. 2024 Apr:368:170-183. PMID: 38382811
- 51. Jiabin Zhang, Xiaodie Chen, et al. "3D Printing of a Vascularized Mini‐Liver Based on the Size‐Dependent Functional Enhancements of Cell Spheroids for Rescue of Liver Failure." Adv Sci (Weinh). 2024 Feb 21:e2309899. PMID: 38380546
- 52. Jun Luo, Ping Li, et al. "SLC15A3 plays a crucial role in pulmonary fibrosis by regulating macrophage oxidative stress." Cell Death Differ. 2024 Feb 19. PMID: 38374230
- 53. Rongrong Xuan, et al. "Gut microbiota-derived trimethylamine N-Oxide: a novel target for the treatment of preeclampsia." Gut Microbes. 2024 Jan-Dec;16(1):2311888. PMID: 38351748
- 54. Biao He, Tingsong Hu, et al. "Isolation, characterization, and circulation sphere of a filovirus in fruit bats." Proc Natl Acad Sci U S A. 2024 Feb 13;121(7):e2313789121. PMID: 38335257
- 55. Chun-Wei Chen, et al. "A novel class of inhibitors that disrupts the stability of integrin heterodimers identified by CRISPR-tiling-instructed genetic screens." Nat Struct Mol Biol. 2024 Mar;31(3):465-475. PMID: 38316881
- 56. Jianhua Cheng, Weiyan Xie, et al. "Drug resistance mechanisms in dopamine agonist-resistant prolactin pituitary neuroendocrine tumors and exploration for new drugs." Drug Resist Updat. 2024 Mar:73:101056. PMID: 38277755
- 57. Fenghuang Zhan, et al. "Bispecific BCMA/CD24 CAR-T cells control multiple myeloma growth." Nat Commun. 2024 Jan 19;15(1):615. PMID: 38242888
- 58. Sanhong Liu, Weidong Zhang, et al. "Benzosceptrin C induces lysosomal degradation of PD-L1 and promotes antitumor immunity by targeting DHHC3." ell Rep Med. 2024 Feb 20;5(2):101357. PMID: 38237597
- 59. Xiaodan Meng, et al. "LncRNA AL139294.1 can be transported by extracellular vesicles to promote the oncogenic behaviour of recipient cells through activation of the Wnt and NF-κB2 pathways in non-small-cell lung cancer." J Exp Clin Cancer Res. 2024 Jan 16;43(1):20. PMID: 38229152
- 60. Tanchen Ren, et al. "Enhancing aortic valve drug delivery with PAR2-targeting magnetic nano-cargoes for calcification alleviation." Nat Commun. 2024 Jan 16;15(1):557. PMID: 38228638
- 61. Haiteng Deng, et al. "Flavonoid 4, 4′-dimethoxychalcone selectively eliminates senescent cells via activating ferritinophagy." Redox Biol. 2024 Feb:69:103017. PMID: 38176315
- 62. Bowen Dong, Yangyang Jiang, et al. "Selenomethionine alleviates decabromodiphenyl ether-induced oxidative stress and ferroptosis via the NRF2/GPX4 pathway in the chicken brain." J Hazard Mater. 2024 Mar 5:465:133307. PMID: 38154185
- 63. Chen Wu, et al. "Molecular mechanism of human ISG20L2 for the ITS1 cleavage in the processing of 18S precursor ribosomal RNA." Nucleic Acids Res. 2024 Feb 28;52(4):1878-1895. PMID: 38153123
- 64. Lei Fan, et al. "Targeting the cGAS‐STING Pathway Inhibits Peripheral T‐cell Lymphoma Progression and Enhances the Chemotherapeutic Efficacy." Adv Sci (Weinh). 2024 Mar;11(10):e2306092. PMID: 38145335
- 65. Zhijing He, He Zhou, et al. "A bimetallic dual-targeting nanoplatform for combinational ferroptosis activation/epigenetic regulation/photothermal therapy against breast cancer and tumor microenvironment remodeling." Chemical Engineering Journal Volume 479, 1 January 2024, 147466.
- 66. Tony Jun Huang, et al. "Cellular immunity analysis by a modular acoustofluidic platform: CIAMAP." Sci Adv. 2023 Dec 22;9(51):eadj9964. PMID: 38134285
- 67. Zhenyan Miao, Jifei Li, et al. "Hsa_circ_0136666 stimulates gastric cancer progression and tumor immune escape by regulating the miR-375/PRKDC Axis and PD-L1 phosphorylation." Mol Cancer. 2023 Dec 13;22(1):205. PMID: 38093288
- 68. Xuan Wang, Aobo Liu, et al. "Additively Manufactured Zn‐2Mg Alloy Porous Scaffolds with Customizable Biodegradable Performance and Enhanced Osteogenic Ability." Adv Sci (Weinh). 2023 Dec 7:e2307329. PMID: 38059810
- 69. Zhenzhou Chen, Yidan Li, et al. "CircGPRC5A enhances colorectal cancer progress by stabilizing PPP1CA and inducing YAP dephosphorylation." J Exp Clin Cancer Res. 2023 Dec 6;42(1):334. PMID: 38057879
- 70. Shangyou Zheng, Qing Tian, et al. "Extracellular vesicle-packaged circBIRC6 from cancer-associated fibroblasts induce platinum resistance via SUMOylation modulation in pancreatic cancer." J Exp Clin Cancer Res. 2023 Nov 28;42(1):324. PMID: 38012734
- 71. Mingyang Liu, Ruizhe Zhang, et al. "Erythrocyte‐Leveraged Oncolytic Virotherapy (ELeOVt): Oncolytic Virus Assembly on Erythrocyte Surface to Combat Pulmonary Metastasis and Alleviate Side Effects." Adv Sci (Weinh). 2023 Nov 23:e2303907. PMID: 37997186
- 72. Zhi Chen, Chan Chen, et al. "HILPS, a long noncoding RNA essential for global oxygen sensing in humans." Sci Adv. 2023 Nov 24;9(47):eadi1867. PMID: 37992175
- 73. Shan Gao, Meng Liu, et al. "Biomimetic biomineralization nanoplatform-mediated differentiation therapy and phototherapy for cancer stem cell inhibition and antitumor immunity activation." Asian J Pharm Sci. 2023 Sep;18(5):100851. PMID: 37915760
- 74. Zijuan Wu, Xiaoling Zuo, et al. "m6A‐Modified circTET2 Interacting with HNRNPC Regulates Fatty Acid Oxidation to Promote the Proliferation of Chronic Lymphocytic Leukemia." Adv Sci (Weinh). 2023 Dec;10(34):e2304895. PMID: 37821382
- 75. Jin Wu, Yingying Han, et al. "Deficient chaperone-mediated autophagy facilitates LPS-induced microglial activation via regulation of the p300/NF-κB/NLRP3 pathway." Sci Adv. 2023 Oct 6;9(40):eadi8343. PMID: 37801503
- 76. Juan Wang, Qianhao Yang, et al. "Geometric Angles and Gene Expression in Cells for Structural Bone Regeneration." Adv Sci (Weinh). 2023 Nov;10(32):e2304111. PMID: 37775309
- 77. Jing Sun, Haonan He, et al. "Protein fibers with self-recoverable mechanical properties via dynamic imine chemistry." Nat Commun. 2023 Sep 2;14(1):5348. PMID: 37660126
- 78. Shao-Qi Zhang, Qiao Deng, et al. "Cell type-specific NRBF2 orchestrates autophagic flux and adult hippocampal neurogenesis in chronic stress-induced depression." Cell Discov. 2023 Aug 29;9(1):90. PMID: 37644025
- 79. Chang Zhao, Heli Wang, et al. "Biased allosteric activation of ketone body receptor HCAR2 suppresses inflammation." Mol Cell. 2023 Sep 7;83(17):3171-3187.e7. PMID: 37597514
- 80. Zicheng Deng, Wen Gao, et al. "Fluorinated amphiphilic Poly (β-Amino ester) nanoparticle for highly efficient and specific delivery of nucleic acids to the Lung capillary endothelium." Bioact Mater. 2023 Aug 7;31:1-17. PMID: 37593494
- 81. Wenyu Dai, Rui Shu, et al. "Engineered Bio-Heterojunction Confers Extra- and Intracellular Bacterial Ferroptosis and Hunger-Triggered Cell Protection for Diabetic Wound Repair." Adv Mater. 2024 Mar;36(9):e2305277. PMID: 37526952
- 82. Teng Xu, Yuemei Yang, et al. "TNFAIP2 confers cisplatin resistance in head and neck squamous cell carcinoma via KEAP1/NRF2 signaling." J Exp Clin Cancer Res. 2023 Aug 1;42(1):190. PMID: 37525222
- 83. Chaolong Wang, Jian Wang, et al. "A natural gene drive system confers reproductive isolation in rice." Cell. 2023 Aug 17;186(17):3577-3592.e18. PMID: 37499659
- 84. Shaoqi Yang, Yuheng Sun, et al. "Single-cell transcriptome sequencing–based analysis: probing the mechanisms of glycoprotein NMB regulation of epithelial cells involved in silicosis." Part Fibre Toxicol. 2023 Jul 19;20(1):29. PMID: 37468937
- 85. Ziqing Yang, Shaomin Zou, et al. "ACTL6A protects gastric cancer cells against ferroptosis through induction of glutathione synthesis." Nat Commun. 2023 Jul 13;14(1):4193. PMID: 37443154
- 86. Jingxia Han, Yu Sun, et al. "Echinacoside-Zinc Nanomaterial Inhibits Skin Glycation by Suppressing the Transcriptional Activation of the Receptor for Advanced Glycation End-Products." ACS Nano. 2023 Jul 25;17(14):14123-14135. PMID: 37403876
- 87. Xiong Guo, Fangfang Xiu, et al. "20(R)-ginsenoside Rg3-loaded polyurethane/marine polysaccharide based nanofiber dressings improved burn wound healing potentials." Carbohydr Polym. 2023 Oct 1:317:121085. PMID: 37364955
- 88. Xiaoyun Yang, Jiaxu Wang, et al. "Structural and biochemical insights into the molecular mechanism of TRPT1 for nucleic acid ADP-ribosylation." Nucleic Acids Res. 2023 Aug 11;51(14):7649-7665. PMID: 37334830
- 89. Yu Zhang, Xiyou Du, et al. "A Vanadium-Based Nanoplatform Synergizing Ferroptotic-like Therapy with Glucose Metabolism Intervention for Enhanced Cancer Cell Death and Antitumor Immunity." ACS Nano. 2023 Jun 5. PMID: 37272777
- 90. Ya-Rui Hou, Li-Ting Diao, et al. "The Conserved LncRNA DIO3OS Restricts Hepatocellular Carcinoma Stemness by Interfering with NONO‐Mediated Nuclear Export of ZEB1 mRNA." Adv Sci (Weinh). 2023 Aug;10(23):e2301983. PMID: 37271897
- 91. Dingcheng Shen, Jinxin Lin, et al. "RNA demethylase ALKBH5 promotes colorectal cancer progression by posttranscriptional activation of RAB5A in an m6A‐YTHDF2‐dependent manner." Clin Transl Med. 2023 May;13(5):e1279. PMID: 37203239
- 92. Wenxia Wei, Baifu Qin, et al. "FBXW7β loss-of-function enhances FASN-mediated lipogenesis and promotes colorectal cancer growth." Signal Transduct Target Ther. 2023 May 19;8(1):187. PMID: 37202390
- 93. Bei Wang, Arabella H Wan, et al. "Identification of indocyanine green as a STT3B inhibitor against mushroom α-amanitin cytotoxicity." Nat Commun. 2023 May 16;14(1):2241. PMID: 37193694
- 94. Zhenbao Zhang, Aobo Liu, et al. "A drug-loaded composite coating to improve osteogenic and antibacterial properties of Zn–1Mg porous scaffolds as biodegradable bone implants." Bioact Mater. 2023 Apr 28:27:488-504. PMID: 37180641
- 95. Yao Lin, Jingchen Xu, et al. "Drug-free and non-crosslinked chitosan/hyaluronic acid hybrid hydrogel for synergistic healing of infected diabetic wounds." Carbohydr Polym. 2023 Aug 15:314:120962. PMID: 37173016
- 96. Jiayin Yu, Zhihao Guo, et al. "Gastric Acid‐Responsive ROS Nanogenerators for Effective Treatment ofHelicobacter pyloriInfection without Disrupting Homeostasis of Intestinal Flora." Adv Sci (Weinh). 2023 Jul;10(20):e2206957. PMID: 37127895
- 97. Ziqiang Chu, Qilin Huang, et al. "Novel neutrophil extracellular trap-related mechanisms in diabetic wounds inspire a promising treatment strategy with hypoxia-challenged small extracellular vesicles." Bioact Mater. 2023 Apr 14:27:257-270. PMID: 37122894
- 98. Haohan Liu, Deliang Fang, et al. "Circular MTHFD2L RNA-encoded CM-248aa inhibits gastric cancer progression by targeting the SET-PP2A interaction." Mol Ther. 2023 Jun 7;31(6):1739-1755. PMID: 37101395
- 99. Lei Chen, Wenjing Zhang, et al. "RBM4 dictates ESCC cell fate switch from cellular senescence to glutamine-addiction survival through inhibiting LKB1-AMPK-axis." Signal Transduct Target Ther. 2023 Apr 21;8(1):159. PMID: 37080995
- 100. Yanrong Su, Yufen Huang, et al. "Study on the Role of an Erythrocyte Membrane‐Coated Nanotheranostic System in Targeted Immune Regulation of Alzheimer's Disease." Adv Sci (Weinh). 2023 Jun;10(18):e2301361. PMID: 37075744
- 101. Yanfei Zhou, Gang He, et al. "Nanoplastics induces oxidative stress and triggers lysosome-associated immune-defensive cell death in the earthworm Eisenia fetida." Environ Int. 2023 Apr:174:107899. PMID: 37054650
- 102. Yusen Hao, Hui Li, et al. "Bio‐Inspired Antioxidant Heparin‐Mimetic Peptide Hydrogel for Radiation‐Induced Skin Injury Repair." Adv Healthc Mater. 2023 Aug;12(20):e2203387. PMID: 36934301
- 103. Yanan Zhang, Renwang Sheng, et al. "Silk Fibroin and Sericin Differentially Potentiate the Paracrine and Regenerative Functions of Stem Cells Through Multiomics Analysis." Adv Mater. 2023 May;35(20):e2210517. PMID: 36915982
- 104. Hao Yan, Sarah Forward, et al. "All-natural-molecule, bioluminescent photodynamic therapy results in complete tumor regression and prevents metastasis." Biomaterials. 2023 May:296:122079. PMID: 36889146
- 105. Shengjie Sun, Mian Yu, et al. "Nrf2 silencing amplifies DNA photooxidative damage to activate the STING pathway for synergistic tumor immunotherapy." Biomaterials. 2023 May:296:122068. PMID: 36868032
- 106. You S, Xiang Y, et al. "High cell density and high-resolution 3D bioprinting for fabricating vascularized tissues." Sci Adv 2023 Feb 22;9(8) PMID: 36812321
- 107. Zhechuan Zhang, Yuanfeng Zhang, et al. "P4HA3 promotes clear cell renal cell carcinoma progression via the PI3K/AKT/GSK3β pathway." Med Oncol. 2023 Jan 2;40(2):70. PMID: 36588128
- 108. Zaizhou Liu, Kaige Chen, et al. "A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy." Cell Res. 2023 Jan; 33(1): 55–70. PMID: 36588115
- 109. Chuchu Lin, Chenyi Huang, et al. "Biodegradable calcium sulfide-based nanomodulators for H2S-boosted Ca2+-involved synergistic cascade cancer therapy." Acta Pharm Sin B. 2022 Dec;12(12):4472-4485. PMID: 36561996
- 110. J. Li, Q. Tian, et al. "A novel liposome-loaded injectable hydrogel for enhanced treatment of choroidal neovascularization by sub-tenon's injection." Materials Today Nano. Volume 20, December 2022, 100264.
- 111. Cheng Wei, Xiaoyang Zhang, et al. "LncRNA HOXA11-AS promotes glioma malignant phenotypes and reduces its sensitivity to ROS via Tpl2-MEK1/2-ERK1/2 pathway." Cell Death Dis. 2022 Nov 9;13(11):942. PMID: 36351895
- 112. Zheng Liu, Xing Luo, et al. "Enzyme-Enhanced Codelivery of Doxorubicin and Bcl-2 Inhibitor by Electrospun Nanofibers for Synergistic Inhibition of Prostate Cancer Recurrence." Pharmaceuticals (Basel). 2022 Oct 10;15(10):1244. PMID: 36297356
- 113. Qiong Wang, Junxiu Chen, et al. "MiR-29c-3p and MiR-223-3p regulate the proliferation and drug resistance of oral squamous cell carcinoma by targeting ANGPTL4." Front Oral Maxillofac Med 2022. Vol 4 (December 30, 2022).
- 114. Dejuan Sun, Yueying Yang, et al. "Identification of ADP-ribosylation factor 6 as the cellular target of withangulatin A against TNBC cells by ferroptosis." Research Square. October 14th, 2022.
- 115. Haiyan Wang, Hanqing Lin, et al. "miR-34a/DRP-1-mediated mitophagy participated in cisplatin-induced ototoxicity via increasing oxidative stress." Research Square. September 28th, 2022.
- 116. Qianying Jia, Qinggong Jia, et al. "A promoting nitric oxide-releasing coating containing copper ion on ZE21B alloy for potential vascular stent application." Journal of Magnesium and Alloys. 28 September 2022.
- 117. Qin Tang, Yue-ming Chen, et al. "Increased Expression of NXPH4 Correlates with Immune Cell Infiltration and Unfavorable Prognosis in Hepatocellular Carcinoma." J Oncol. 2022 Oct 6;2022:5005747. PMID: 36245978
- 118. Yuan Li, Qingya Dang, et al. "Restoration of Mitochondrial Function Is Essential in the Endothelium-Dependent Vasodilation Induced by Acacetin in Hypertensive Rats." Int J Mol Sci. 2022 Sep 26;23(19):11350. PMID: 36232649
- 119. Yufei Long, Tuotuo Chong, et al. "FOXD1-dependent RalA-ANXA2-Src complex promotes CTC formation in breast cancer." J Exp Clin Cancer Res. 2022 Oct 13;41(1):301. PMID: 36229838
- 120. Chen Chen, Heng Zhang, et al. "Shenxian-Shengmai Oral Liquid Evoke Autophagy of Fibroblast to Attenuate Sinoatrial Node Fibrosis in Sick Sinus Syndrome Mice via the AKT/mTOR Pathway." Evid Based Complement Alternat Med. 2022 Sep 28;2022:5219277. PMID: 36212944
- 121. Xiaolong Tang, Yahang Liang, et al. "Upregulation of CRABP2 by TET1-mediated DNA hydroxymethylation attenuates mitochondrial apoptosis and promotes oxaliplatin resistance in gastric cancer." Cell Death Dis. 2022 Oct 4;13(10):848. PMID: 36195596
- 122. Jun-Dan Wang, Jue-Qiong Xu, et al. "Mutant C/EBPα p30 alleviates immunosuppression of CD8+ T cells by inhibiting autophagy-associated secretion of IL-1β in AML." Cell Prolif. 2022 Dec;55(12):e13331. PMID: 36124714
- 123. Wei Zhu, Xiaofen Zhang, et al. "Profiles of Acetylation Regulation Genes Contribute to Malignant Progression and Have a Clinical Prognostic Impact on Liver Cancer." Dis Markers. 2022 Sep 10;2022:1724301. PMID: 36124029
- 124. Ruo-Wen Xiao, Fang Wang, et al. "Rare POLN mutations confer risk for familial nasopharyngeal carcinoma through weakened Epstein-Barr virus lytic replication." EBioMedicine. 2022 Oct;84:104267. PMID: 36116213
- 125. LIJUN LI, ZHIHAO WEN, et al. "LIS1 interacts with CLIP170 to promote tumor growth and metastasis via the Cdc42 signaling pathway in salivary gland adenoid cystic carcinoma." Int J Oncol. 2022 Oct;61(4):129. PMID: 36102310
- 126. Lijuan Bian, Xi Rui, et al. "Profile of chimeric RNAs and TMPRSS2-ERG e2e4 isoform in neuroendocrine prostate cancer." Cell Biosci. 2022 Sep 10;12(1):153. PMID: 36088396
- 127. Zijuan Wu, Danling Gu, et al. "CircRIC8B regulates the lipid metabolism of chronic lymphocytic leukemia through miR199b-5p/LPL axis." Exp Hematol Oncol. 2022 Sep 5;11(1):51. PMID: 36064433
- 128. Anne Behre, Joshua W Tashman, et al. "3D Bioprinted Patient‐Specific Extracellular Matrix Scaffolds for Soft Tissue Defects." Adv Healthc Mater. 2022 Sep 5;e2200866. PMID: 36063047
- 129. Peng Ye, Zhanhu Mi, et al. "miR-3960 from Mesenchymal Stem Cell-Derived Extracellular Vesicles Inactivates SDC1/Wnt/ β-Catenin Axis to Relieve Chondrocyte Injury in Osteoarthritis by Targeting PHLDA2." Stem Cells Int. 2022 Aug 25;2022:9455152. PMID: 36061148
- 130. Yao J, Tang S, et al. "Isoginkgetin, a potential CDK6 inhibitor, suppresses SLC2A1/GLUT1 enhancer activity to induce AMPK-ULK1-mediated cytotoxic autophagy in hepatocellular carcinoma." Autophagy, 2023, 19(4): 1221-1238. PMID: 36048765
- 131. Jierong Chen, Lixue Cao, et al. "HDAC8 Promotes Liver Metastasis of Colorectal Cancer via Inhibition of IRF1 and Upregulation of SUCNR1." Oxid Med Cell Longev. 2022 Aug 16;2022:2815187. PMID: 36035205
- 132. Caiji Lin, Zheng Zeng, et al. "Naringenin suppresses epithelial ovarian cancer by inhibiting proliferation and modulating gut microbiota." Phytomedicine. 2022 Nov;106:154401. PMID: 36029647
- 133. Qing Zhang, Yue Zhou, et al. "Low-dose orlistat promotes the therapeutic effect of oxaliplatin in colorectal cancer." Biomed Pharmacother. 2022 Sep;153:113426. PMID: 36017794
- 134. Xin Ming, Huan Chen, et al. "Porcine Enteric Coronavirus PEDV Induces the ROS-ATM and Caspase7-CAD-γH2AX Signaling Pathways to Foster Its Replication." Viruses. 2022 Aug 15;14(8):1782. PMID: 36016404
- 135. Wang Liao, Xinyi Cao, et al. "Pea Protein-Derived Peptides Inhibit Hepatic Glucose Production via the Gluconeogenic Signaling in the AML-12 Cells." Int J Environ Res Public Health. 2022 Aug 18;19(16):10254. PMID: 36011893
- 136. Xin Shen, Weiwen Zhu, et al. "Macrophage miR-149-5p induction is a key driver and therapeutic target for BRONJ." JCI Insight. 2022 Aug 22;7(16):e159865. PMID: 35993364
- 137. Qiang Wang, Chen Chen, et al. "APAF1‐Binding Long Noncoding RNA Promotes Tumor Growth and Multidrug Resistance in Gastric Cancer by Blocking Apoptosome Assembly." Adv Sci (Weinh). 2022 Oct;9(28):e2201889. PMID: 35975461
- 138. Junyu Zheng, Cong Li, et al. "A 5`-tRNA Derived Fragment NamedtiRNA-Val-CAC-001 Works as a Suppressor in Gastric Cancer." Cancer Manag Res. 2022 Aug 4;14:2323-2337. PMID: 35958946
- 139. Jing Han, Gang-Hua Feng, et al. "Classifying mild cognitive impairment and Alzheimer's disease by constructing a 14-gene diagnostic model." Am J Transl Res. 2022 Jul 15;14(7):4477-4492. PMID: 35958496
- 140. Xiaoli Liu, Huikun Zhang, et al. "Knockdown of Girdin Induced Apoptosis of Glioblastoma Cells via the Mitochondrion Signaling Pathway." Neuroscience. 2022 Sep 15;500:95-105. PMID: 35952993
- 141. Li‑Ming Xu, Ya‑Jing Yuan, et al. "LINC00665 knockdown confers sensitivity in irradiated non-small cell lung cancer cells through the miR-582-5p/UCHL3/AhR axis." J Transl Med. 2022 Aug 2;20(1):350. PMID: 35918714
- 142. Chunhua Tian, Jing Su, et al. "lncRNA NBAT1 Inhibits Cell Metastasis and Promotes Apoptosis in Endometrial Cancer by Sponging miR-21-5p to Regulate PTEN." Comput Math Methods Med. 2022 Jul 20;2022:9304392. PMID: 35912140
- 143. Xiaoyu Feng, Wenfeng Hu, et al. "Taurine Ameliorates Iron Overload-Induced Hepatocyte Injury via the Bcl-2/VDAC1-Mediated Mitochondrial Apoptosis Pathway." Oxid Med Cell Longev. 2022 Jul 16;2022:4135752. PMID: 35879990
- 144. Qi Dong, Dan Zu, et al. "Construction of antibacterial nano-silver embedded bioactive hydrogel to repair infectious skin defects." Biomater Res. 2022 Jul 25;26(1):36. PMID: 35879746
- 145. Thomas Später, Marisa Assunção, et al. "Engineering microparticles based on solidified stem cell secretome with an augmented pro-angiogenic factor portfolio for therapeutic angiogenesis." Bioact Mater. 2022 Apr 2;17:526-541. PMID: 35846945
- 146. Can Cui, Yuting Pan, et al. "Eltrombopag binds SDC4 directly and enhances MAPK signaling and macropinocytosis in cancer cells." Am J Cancer Res. 2022 Jun 15;12(6):2697-2710. PMID: 35812066
- 147. Zijuan Wu, Luqiao Wang, et al. "Exploring the significance of PAK1 through chromosome conformation signatures in ibrutinib-resistant chronic lymphocytic leukaemia." Mol Oncol. 2022 Aug;16(16):2920-2935. PMID: 35811334
- 148. Yang Liu, Libo He, et al. "Pharmacological inhibition of sphingolipid synthesis reduces ferroptosis by stimulating the HIF-1 pathway." iScience. 2022 Jun 6;25(7):104533. PMID: 35784791
- 149. Chengtao Sun, Mengzhen Li, et al. "IDO1 plays a tumor-promoting role via MDM2-mediated suppression of the p53 pathway in diffuse large B-cell lymphoma." Cell Death Dis. 2022 Jun 27;13(6):572. PMID: 35760783
- 150. Di Zhao, Chao Shi, et al. "Multifunctional Gel Films of Marine Polysaccharides Cross-Linked with Poly-Metal Ions for Wound Healing." Pharmaceuticals (Basel). 2022 Jun 15;15(6):750. PMID: 35745669
- 151. Weibo Zhong, Kaihui Wu, et al. "Gut dysbiosis promotes prostate cancer progression and docetaxel resistance via activating NF-κB-IL6-STAT3 axis." Microbiome. 2022 Jun 16;10(1):94. PMID: 35710492
- 152. Ruili Guan, Changhao Yang, et al. "Dehydroepiandrosterone alleviates hypoxia-induced learning and memory dysfunction by maintaining synaptic homeostasis." CNS Neurosci Ther. 2022 Sep;28(9):1339-1350. PMID: 35703574
- 153. Zhicheng Cao, Hongmei Wang, et al. "Silk-based hydrogel incorporated with metal-organic framework nanozymes for enhanced osteochondral regeneration." Bioact Mater. 2022 May 31;20:221-242. PMID: 35702612
- 154. Yanlin Wu, Xuan Li, et al. "Multiscale design of stiffening and ROS scavenging hydrogels for the augmentation of mandibular bone regeneration." Bioact Mater. 2022 May 23;20:111-125. PMID: 35663335
- 155. Haiyan Xing, Qiang Liu, et al. "Cadmium mediates pyroptosis of human dermal lymphatic endothelial cells in a NLRP3 inflammasome-dependent manner." J Toxicol Sci. 2022;47(6):237-247. PMID: 35650140
- 156. Jianjun Qi, Zihua Zeng, et al. "Aptamer-Gemcitabine Conjugates with Enzymatically Cleavable Linker for Targeted Delivery and Intracellular Drug Release in Cancer Cells." Pharmaceuticals (Basel). 2022 Apr 30;15(5):558. PMID: 35631384
- 157. Hongjin Chen, Yuchen Jiang, et al. "Curcumin Derivative C66 Suppresses Pancreatic Cancer Progression through the Inhibition of JNK-Mediated Inflammation." Molecules. 2022 May 11;27(10):3076. PMID: 35630552
- 158. Jieping Zhang, Shaomin Zou, et al. "3,3'-Diindolylmethane Enhances Fluorouracil Sensitivity via Inhibition of Pyrimidine Metabolism in Colorectal Cancer." Metabolites. 2022 Apr 30;12(5):410. PMID: 35629914
- 159. Wei Wang, Xiaolong Liang, et al. "NOX4 blockade suppresses titanium nanoparticle-induced bone destruction via activation of the Nrf2 signaling pathway." J Nanobiotechnology. 2022 May 23;20(1):241. PMID: 35606794
- 160. Qing Liu, Qiyao Li, et al. "circ-Pank1 promotes dopaminergic neuron neurodegeneration through modulating miR-7a-5p/α-syn pathway in Parkinson's disease." Cell Death Dis. 2022 May 19;13(5):477. PMID: 35589691
- 161. Yu Cai, Cuixi Wu, et al. "Enhanced osteoarthritis therapy by nanoengineered mesenchymal stem cells using biomimetic CuS nanoparticles loaded with plasmid DNA encoding TGF-β1." Bioact Mater. 2022 May 2;19:444-457. PMID: 35574050
- 162. He Ding, Zhiqiang Li, et al. "FTO Alleviates CdCl2-Induced Apoptosis and Oxidative Stress via the AKT/Nrf2 Pathway in Bovine Granulosa Cells." Int J Mol Sci. 2022 Apr 29;23(9):4948. PMID: 35563339
- 163. Yanxue Wang, Shuo Luan, et al. "The Combined Use of Platelet-Rich Plasma Clot Releasate and Allogeneic Human Umbilical Cord Mesenchymal Stem Cells Rescue Glucocorticoid-Induced Osteonecrosis of the Femoral Head." Stem Cells Int. 2022 May 2;2022:7432665. PMID: 35547633
- 164. Jianqiang Zhu, Leyi Liu, et al. "Biotransformation of graphene oxide within lung fluids could intensify its synergistic biotoxicity effect with cadmium by inhibiting cellular efflux of cadmium." Environ Pollut. 2022 Aug 1;306:119421. PMID: 35533959
- 165. Luqiao Wang, Zijuan Wu, et al. "Single-cell profiling-guided combination therapy of c-Fos and histone deacetylase inhibitors in diffuse large B-cell lymphoma." Clin Transl Med. 2022 May;12(5):e798. PMID: 35522945
- 166. Xi Wang, Mengmeng Zhang, et al. "Exosomal AFAP1-AS1 binds to microRNA-15a-5p to promote the proliferation, migration, and invasion of ectopic endometrial stromal cells in endometriosis." Reprod Biol Endocrinol. 2022 May 5;20(1):77. PMID: 35513844
- 167. Haojie Chen, Jia Luo, et al. "Non-drug efflux function of ABCC5 promotes enzalutamide resistance in castration-resistant prostate cancer via upregulation of P65/AR-V7." Cell Death Discov. 2022 May 3;8(1):241. PMID: 35504877
- 168. Wei Yu, Weidong Liu, et al. "High Level of Uric Acid Promotes Atherosclerosis by Targeting NRF2-Mediated Autophagy Dysfunction and Ferroptosis." Oxid Med Cell Longev. 2022 Apr 18;2022:9304383. PMID: 35480874
- 169. Tianli Wu, Hui Tang, et al. "METTL3-m6 A methylase regulates the osteogenic potential of bone marrow mesenchymal stem cells in osteoporotic rats via the Wnt signalling pathway." Cell Prolif. 2022 May;55(5):e13234. PMID: 35470497
- 170. Dandan Feng, Jiang Li, et al. "DDX3X alleviates doxorubicin-induced cardiotoxicity by regulating Wnt/β-catenin signaling pathway in an in vitro model." J Biochem Mol Toxicol. 2022 Aug;36(8):e23077. PMID: 35467791
- 171. Xinyu Zhou, Nanqu Huang, et al. "Icaritin attenuates 6-OHDA-induced MN9D cell damage by inhibiting oxidative stress." PeerJ. 2022 Apr 12;10:e13256. PMID: 35433120
- 172. Chang Kong, Xuqing Ni, et al. "ICA69 aggravates ferroptosis causing septic cardiac dysfunction via STING trafficking." Cell Death Discov. 2022 Apr 9;8(1):187. PMID: 35397620
- 173. Xiaohua Zhu, YingYing Xie, et al. "NAP1L1 promotes tumor proliferation through HDGF/C-JUN signaling in ovarian cancer." BMC Cancer. 2022 Mar 29;22(1):339. PMID: 35351053
- 174. Zaiyong Zhang, Jianhao Li, et al. "Regulatory Mechanism of circEIF4G2 Targeting miR-26a in Acute Myocardial Infarction." J Healthc Eng. 2022 Mar 16;2022:5308372. PMID: 35340248
- 175. Qingmei Zhong, Kun Zhang, et al. "In situ ratiometric SERS imaging of intracellular protease activity for subtype discrimination of human breast cancer." Biosens Bioelectron. 2022 Jul 1;207:114194. PMID: 35325718
- 176. Bopei Li, Yeyang Chen, et al. "Tumor-derived extracellular vesicles shuttle c-Myc to promote gastric cancer growth and metastasis via the KCNQ1OT1/miR-556-3p/CLIC1 axis." Cell Death Dis. 2022 Mar 8;13(3):217. PMID: 35260554
- 177. Haixia Wu, Youliang Yan, et al. "miR-4324 inhibits ovarian cancer progression by targeting FEN1." J Ovarian Res. 2022 Mar 4;15(1):32. PMID: 35246224
- 178. Ying Liu, Guangwei Ma, et al. "Global chromosome rearrangement induced by CRISPR-Cas9 reshapes the genome and transcriptome of human cells." Nucleic Acids Res. 2022 Apr 8;50(6):3456-3474. PMID: 35244719
- 179. Nan Zhang, Yan Shen, et al. "The m6A reader IGF2BP3 promotes acute myeloid leukemia progression by enhancing RCC2 stability." Exp Mol Med. 2022 Feb;54(2):194-205. PMID: 35217832
- 180. Xiaowu Ma, Hongkai Zhuang, et al. "SLC39A1 Overexpression is Associated with Immune Infiltration in Hepatocellular Carcinoma and Promotes Its Malignant Progression." J Hepatocell Carcinoma. 2022 Feb 15;9:83-98. PMID: 35211427
- 181. Zongyi Liu, Huanyu Xiang, et al. "Revealing potential anti-fibrotic mechanism of Ganxianfang formula based on RNA sequence." Chin Med. 2022 Feb 18;17(1):23. PMID: 35180857
- 182. Jingjing Wang, Xu Zhu, et al. "Epigenomic reprogramming via HRP2-MINA dictates response to proteasome inhibitors in multiple myeloma with t (4; 14) translocation." J Clin Invest. 2022 Feb 15;132(4):e149526. PMID: 35166240
- 183. Daoyuan Hu, Yunlong Ge, et al. "Upregulated IGFBP3 with Aging Is Involved in Modulating Apoptosis, Oxidative Stress, and Fibrosis: A Target of Age-Related Erectile Dysfunction." Oxid Med Cell Longev. 2022 Feb 3;2022:6831779. PMID: 35154570
- 184. Bin Wang, Jing Zhang, et al. "Protein disulfide isomerases (PDIs) negatively regulate ebolavirus structural glycoprotein expression in the endoplasmic reticulum (ER) via the autophagy-lysosomal pathway." Autophagy. 2022 Oct;18(10):2350-2367. PMID: 35130104
- 185. Zhaoyi Pan, Yujie Feng, et al. "MERS-CoV nsp1 impairs the cellular metabolic processes by selectively downregulating mRNAs in a novel granules." Virulence. 2022 Dec;13(1):355-369. PMID: 35129074
- 186. Jianjun Ma, Xiaoxue Shi, et al. "MicroRNA-181a-2-3p shuttled by mesenchymal stem cell-secreted extracellular vesicles inhibits oxidative stress in Parkinson's disease by inhibiting EGR1 and NOX4." Cell Death Discov. 2022 Jan 24;8(1):33. PMID: 35075150
- 187. MAHA ABDULLA, THAMER BIN TRAIKI, et al. "Targeting MUCL1 protein inhibits cell proliferation and EMT by deregulating β‑catenin and increases irinotecan sensitivity in colorectal cancer." Int J Oncol. 2022 Mar;60(3):22. PMID: 35059735
- 188. Jingjing Zhang, Yun Li, et al. "Genome-wide CRISPR/Cas9 library screen identifies PCMT1 as a critical driver of ovarian cancer metastasis." J Exp Clin Cancer Res. 2022 Jan 15;41(1):24. PMID: 35033172
- 189. Qingwen Li, Jiao Zhang, et al. "MicroRNA-17-3p is upregulated in psoriasis and regulates keratinocyte hyperproliferation and pro-inflammatory cytokine secretion by targeting CTR9." Eur J Histochem. 2022 Jan 12;66(1):3275. PMID: 35016493
- 190. Lin Liu, Yongwu Yang, et al. "Giardia duodenalis and Its Secreted PPIB Trigger Inflammasome Activation and Pyroptosis in Macrophages through TLR4-Induced ROS Signaling and A20-Mediated NLRP3 Deubiquitination." Cells. 2021 Dec 6;10(12):3425. PMID: 34943932
- 191. Na Qiu, Xiaoye Yang, et al. "A molybdenum oxide-based degradable nanosheet for combined chemo-photothermal therapy to improve tumor immunosuppression and suppress distant tumors and lung metastases." J Nanobiotechnology. 2021 Dec 19;19(1):428. PMID: 34923976
- 192. Bo Sun, Xianyu Zheng, et al. "LncRNA LINC01303 Promotes the Progression of Oral Squamous Cell Carcinomas via the miR-429/ZEB1/EMT Axis." J Oncol. 2021 Dec 6;2021:7974012. PMID: 34912458
- 193. Yiming Xu, Dandan Lv, et al. "METTL3 Promotes Lung Adenocarcinoma Tumorigenesis and Inhibits Ferroptosis by Stabilizing SLC7A11 m6A Modification." Research Square. rs-1085921/v1.
- 194. Jian Wang, Qinjiang Bian, et al. "Identification and in vitro validation of prognostic lncRNA signature in head and neck squamous cell carcinoma." Bioengineered. 2021 Dec;12(2):10049-10062. PMID: 34872450
- 195. Xueshan Zhao, Xiaodong Jin, et al. "Silencing of the lncRNA H19 enhances sensitivity to X-ray and carbon-ions through the miR-130a-3p /WNK3 signaling axis in NSCLC cells." Cancer Cell Int. 2021 Dec 4;21(1):644. PMID: 34863180
- 196. YAQI ZHOU, XUESHUANG MEI, et al. "Cordycepin inhibits the proliferation and progression of NPC by targeting the MAPK/ERK and β-catenin pathways." Oncol Lett. 2022 Jan;23(1):20. PMID: 34858524
- 197. Yi Zhou, Jing Li, et al. "Rhophilin rho GTPase binding protein 1-antisense RNA 1 (RHPN1-AS1) promotes ovarian carcinogenesis by sponging microRNA-485-5p and releasing DNA topoisomerase II alpha ( TOP2A)." Bioengineered. 2021 Dec;12(2):12003-12022. PMID: 34787052
- 198. Jiehua He, Ziqiang Chu, et al. "Circular RNA circHERC4 as a novel oncogenic driver to promote tumor metastasis via the miR-556-5p/CTBP2/E-cadherin axis in colorectal cancer." J Hematol Oncol. 2021 Nov 15;14(1):194. PMID: 34781990
- 199. Tian Tian, Fu Hong, et al. "HSD17B6 downregulation predicts poor prognosis and drives tumor progression via activating Akt signaling pathway in lung adenocarcinoma." Cell Death Discov. 2021 Nov 8;7(1):341. PMID: 34750355
- 200. Hongtao Zhen, Peng Du, et al. "LINC00958 promotes bladder cancer carcinogenesis by targeting miR-490-3p and AURKA." BMC Cancer. 2021 Oct 26;21(1):1145. PMID: 34702201
- 201. Xu Zhao, Jizhao Wang, et al. "DLX6-AS1 activated by H3K4me1 enhanced secondary cisplatin resistance of lung squamous cell carcinoma through modulating miR-181a-5p/miR-382-5p/CELF1 axis." Sci Rep. 2021 Oct 25;11(1):21014. PMID: 34697393
- 202. Yong Xie, Yangping Chen, et al. "Adipose Mesenchymal Stem Cell-Derived Exosomes Enhance PC12 Cell Function through the Activation of the PI3K/AKT Pathway." Stem Cells Int. 2021 Oct 15;2021:2229477. PMID: 34691190
- 203. Yan Liang, Chao Qian, et al. "JWA suppresses proliferation in trastuzumab-resistant breast cancer by downregulating CDK12." Cell Death Discov. 2021 Oct 22;7(1):306. PMID: 34686673
- 204. Lei Gao, Xiaolong Tang, et al. "Exosome-transmitted circCOG2 promotes colorectal cancer progression via miR-1305/TGF-β2/SMAD3 pathway." Cell Death Discov. 2021 Oct 11;7(1):281. PMID: 34635639
- 205. Wenjing Zhang, Yu Sun, et al. "RBMS1 regulates lung cancer ferroptosis through translational control of SLC7A11." J Clin Invest. 2021 Nov 15;131(22):e152067. PMID: 34609966
- 206. Wenwen Liu, Yang Zhou, et al. "Glutathione peroxidase 4-dependent glutathione high-consumption drives acquired platinum chemoresistance in lung cancer-derived brain metastasis." Clin Transl Med. 2021 Sep;11(9):e517. PMID: 34586745
- 207. D Cai, S Chen, et al. "Construction of multifunctional porcine acellular dermal matrix hydrogel blended with vancomycin for hemorrhage control, antibacterial action, and tissue repair in infected trauma wounds." Mater Today Bio. 2021 Aug 19;12:100127. PMID: 34585135
- 208. Weian Zhao, Lu Yang, et al. "Cardiac-Specific Gene TNNI3 as a Potential Oncogene for Kidney Cancer and Its Involvement in Wnt Signaling Pathway." Research Square. rs-754351/v1.
- 209. Li-Ming Liu, Qiang Tang, et al. "Arginine Methyltransferase PRMT1 Regulates p53 Activity in Breast Cancer." Life (Basel). 2021 Aug 5;11(8):789. PMID: 34440533
- 210. Yongjian Zhou, Nanqu Huang, et al. "Icaritin protects SH-SY5Y cells transfected with TDP-43 by alleviating mitochondrial damage and oxidative stress." PeerJ. 2021 Aug 10;9:e11978. PMID: 34434670
- 211. Yingnan Liu, Yao Li, et al. "Development and in vivo evaluation of MGF100-1R deletion mutant in an African swine fever virus Chinese strain." Vet Microbiol. 2021 Oct;261:109208. PMID: 34419775
- 212. Yandong Bao, Ying Qiao, et al. "miRNA-27a Transcription Activated by c-Fos Regulates Myocardial Ischemia-Reperfusion Injury by Targeting ATAD3a." Oxid Med Cell Longev. 2021 Aug 8;2021:2514947. PMID: 34413925
- 213. Shaoqian Cui, Lei Zhang. "microRNA-129-5p shuttled by mesenchymal stem cell-derived extracellular vesicles alleviates intervertebral disc degeneration via blockade of LRG1-mediated p38 MAPK activation." J Tissue Eng. 2021 Jul 29;12:20417314211021679. PMID: 34377430
- 214. Chaozhong Peng, Xiao Li, et al. "Rab1A promotes cell proliferation and migration by upregulating Gli1 in colorectal cancer." Sci Rep. 2021 Aug 10;11(1):16243. PMID: 34376787
- 215. Jing Liu, Jiahuan Wang, et al. "MiR-195-5p and miR-205-5p in extracellular vesicles isolated from diabetic foot ulcer wound fluid decrease angiogenesis by inhibiting VEGFA expression." Aging (Albany NY). 2021 Aug 9;13(15):19805-19821. PMID: 34370714
- 216. Lulin Tan, Zhaojun Chen, et al. "MicroRNA Profiling Reveals an Abundant sscmiRNA-148a-3p that Promotes Proliferation and Differentiation during Intramuscular Adipogenesis in Chinese Guizhou Congjiang Pigs Breeds by targeting PPARGC1A." Research Square. rs-818015/v1.
- 217. Zhenyu Zhao, Gen Li, et al. "Capturing Magnesium IonsviaMicrofluidic Hydrogel Microspheres for Promoting Cancellous Bone Regeneration." ACS Nano. 2021 Aug 24;15(8):13041-13054. PMID: 34342981
- 218. Chunyan Wang, Tianli Zhang, et al. "ER-α36 Promotes the Malignant Progression of Cervical Cancer Mediated by Estrogen via HMGA2." Front Oncol. 2021 Jul 14;11:712849. PMID: 34336701
- 219. Rongxue Shao, Liang Zhang, et al. "Autophagy activation promotes the effect of iPSCs-derived NSCs on bladder function restoration after spinal cord injury." Tissue Cell. 2021 Oct;72:101596. PMID: 34333229
- 220. Qingqing Hu, Xiaochu Hu, et al. "Upregulation of SGOL2 Predicts Poor Prognosis and Facilitates Hepatocellular Carcinoma Progression via Dysregulating the Cell Cycle by Directly Activating MAD2." Research Square. rs-560609/v1.
- 221. Bingquan Jiana, Jiaqi Pang, et al. "Autophagy-dependent ferroptosis contributes to cisplatin-induced hearing loss." Toxicol Lett. 2021 Oct 10;350:249-260. PMID: 34302894
- 222. Jian‑Ping Zhang, Wei‑Jing Zhang, et al. "Propofol attenuates lung ischemia/reperfusion injury though the involvement of the MALAT1/microRNA-144/GSK3β axis." Mol Med. 2021 Jul 15;27(1):77. PMID: 34266379
- 223. Qingsong Jiang, Xiaoya He, et al. "d-Alanine metabolic pathway, a potential target for antibacterial drug designing in Enterococcus faecalis." Microb Pathog. 2021 Sep;158:105078. PMID: 34245823
- 224. Guiyuan Guo, Jie Cai. "Rosuvastatin alleviated the liver ischemia reperfusion injury by activating the expression of peroxisome proliferator-activated receptor gamma (PPARγ)." J Bioenerg Biomembr. 2021 Oct;53(5):573-583. PMID: 34235609
- 225. Xiaoyuan Wang, Peng Yang, et al. "LncRNA SNHG14 promotes cell proliferation and invasion in colorectal cancer through modulating miR-519b-3p/DDX5 axis." J Cancer. 2021 Jun 11;12(16):4958-4970. PMID: 34234865
- 226. Wei Zhang, Yanan Zhang, et al. "Enzymatically crosslinked silk-nanosilicate reinforced hydrogel with dual-lineage bioactivity for osteochondral tissue engineering." Mater Sci Eng C Mater Biol Appl. 2021 Aug;127:112215. PMID: 34225867
- 227. Hui Song, Yan Zhang, et al. "Activation of DNA methyltransferase 3a by Epstein-Barr nuclear antigen 1 in gastric carcinoma." Dig Liver Dis. 2022 Jul;54(7):973-983. PMID: 34215536
- 228. Yangfeng Shi, Yiming Xu, et al. "MTHFD2 promotes tumorigenesis and metastasis in lung adenocarcinoma by regulating AKT/GSK-3β/β-catenin signalling." J Cell Mol Med. 2021 Jul;25(14):7013-7027. PMID: 34121323
- 229. Yi Jiang, Ming Shen, et al. "Melatonin Represses Mitophagy to Protect Mouse Granulosa Cells from Oxidative Damage." Biomolecules. 2021 Jun 30;11(7):968. PMID: 34209255
- 230. Zhihan Wang, Kai Guo, et al. "Microbial and genetic-based framework identifies drug targets in inflammatory bowel disease." Theranostics. 2021 Jun 1;11(15):7491-7506. PMID: 34158863
- 231. Guangyu Ji, Wenjuan Zhou, et al. "PCGF1 promotes epigenetic activation of stemness markers and colorectal cancer stem cell enrichment." Cell Death Dis. 2021 Jun 19;12(7):633. PMID: 34148069
- 232. Mengzhen Li, Chengtao Sun, et al. "ISL1 promoted tumorigenesis and EMT via Aurora kinase A-induced activation of PI3K/AKT signaling pathway in neuroblastoma." Cell Death Dis. 2021 Jun 15;12(6):620. PMID: 34131100
- 233. Gaoran Ge, Jiaxiang Bai, et al. "Punicalagin ameliorates collagen-induced arthritis by downregulating M1 macrophage and pyroptosis via NF-κB signaling pathway." Sci China Life Sci. 2022 Mar;65(3):588-603. PMID: 34125371
- 234. Liang Y, Wang J. "Sorafenib-Induced Exosome Secretion Promotes Che-motherapy Resistance in Hepatoma Cell Line." Japanese J Gstro Hepato. 2021; V6(12): 1-7.
- 235. Guanghua Qin, Xuejian Wu. "Circular RNA hsa_circ_0032463 Acts as the Tumor Promoter in Osteosarcoma by Regulating the MicroRNA 498/LEF1 Axis." Mol Cell Biol. 2021 Jul 23;41(8):e0010021. PMID: 34096776
- 236. Hongshuo Zhang, Jia Qi, et al. "O-GlcNAc modification mediates aquaporin 3 to coordinate endometrial cell glycolysis and affects embryo implantation." Journal of Advanced Research.Available online 30 June 2021.
- 237. Chunxia Ren, Xinqing Hao, et al. "Metformin Carbon Dots for Promoting Periodontal Bone Regeneration via Activation of ERK/AMPK Pathway." Adv Healthc Mater. 2021 Jun;10(12):e2100196. PMID: 33987977
- 238. Xiaolie He, Yanjing Zhu, et al. "MgFe-LDH Nanoparticles: A Promising Leukemia Inhibitory Factor Replacement for Self-Renewal and Pluripotency Maintenance in Cultured Mouse Embryonic Stem Cells." Adv Sci (Weinh). 2021 Feb 25;8(9):2003535. PMID: 33977050
- 239. Jing Liu, He Chen, et al. "Cancer selective target degradation by folate-caged PROTACs." J Am Chem Soc. 2021 May 19;143(19):7380-7387. PMID: 33970635
- 240. Wei Li, Junwei Wang, et al. "MicroRNA-543-3p down-regulates inflammation and inhibits periodontitis through KLF6." Biosci Rep. 2021 May 28;41(5):BSR20210138. PMID: 33955459
- 241. Heng Zhang, Miao Hao, et al. "Shenxian-Shengmai Oral Liquid Improves Sinoatrial Node Dysfunction through the PKC/NOX-2 Signaling Pathway." Evid Based Complement Alternat Med. 2021 Apr 10;2021:5572140. PMID: 33936239
- 242. Geng Li, Linghui Zhang. "miR-335-5p aggravates type 2 diabetes by inhibiting SLC2A4 expression." Biochem Biophys Res Commun. 2021 Jun 18;558:71-78. PMID: 33901926
- 243. Ning Li, Xiaoping Li, et al. "Inhibition of Sirtuin 3 prevents titanium particle-induced bone resorption and osteoclastsogenesis via suppressing ERK and JNK signaling." Int J Biol Sci. 2021 Apr 3;17(5):1382-1394. PMID: 33867853
- 244. Keting Bao, Yongyun Li, et al. "Fangchinoline suppresses conjunctival melanoma by directly binding FUBP2 and inhibiting the homologous recombination pathway." Cell Death Dis. 2021 Apr 7;12(4):380. PMID: 33828201
- 245. Xiangli Zhuang, Bo Wu, et al. "Effect of Xingbi Gel Nasal Drops on Fyn-STAT5 Pathway in Nasal Mucosa Fibroblasts of Guinea Pigs with Allergic Rhinitis." Evid Based Complement Alternat Med. 2021 Mar 20;2021:6686815. PMID: 33824677
- 246. Yuzhen Liao, Zhi Zhou, et al. "Cell-friendly photo-functionalized TiO 2 nano-micro-honeycombs for selectively preventing bacteria and platelet adhesion." Mater Sci Eng C Mater Biol Appl. 2021 Apr;123:111996. PMID: 33812616
- 247. Mei-sa Wang, Qiu-shuang Han, et al. "PPARα agonist fenofibrate relieves acquired resistance to gefitinib in non-small cell lung cancer by promoting apoptosis via PPARα/AMPK/AKT/FoxO1 pathway." Acta Pharmacol Sin. 2022 Jan;43(1):167-176. PMID: 33772142
- 248. Yuefei Zhang, Yiqing Li, et al. "Phosphatase Shp2 regulates biogenesis of small extracellular vesicles by dephosphorylating Syntenin." J Extracell Vesicles. 2021 Mar;10(5):e12078. PMID: 33732417
- 249. Yilei Zhang, Robert V Swanda, et al. "mTORC1 couples cyst(e)ine availability with GPX4 protein synthesis and ferroptosis regulation." Nat Commun. 2021 Mar 11;12(1):1589. PMID: 33707434
- 250. Jiancong Lu, Junhong Lin, et al. "MiR-328-3p inhibits lung adenocarcinoma-genesis by downregulation PYCR1." Biochem Biophys Res Commun. 2021 Apr 23;550:99-106. PMID: 33706104
- 251. Xiaohong Pu, Qing Ye, et al. "Typing FGFR2 translocation determines the response to targeted therapy of intrahepatic cholangiocarcinomas." Cell Death Dis. 2021 Mar 11;12(3):256. PMID: 33692336
- 252. Wujing Dai, Han Qu, et al. "Far Upstream Binding Protein 1 (FUBP1) participates in translational regulation of Nrf2 protein under oxidative stress." Redox Biol. 2021 May;41:101906. PMID: 33676361
- 253. Yue Wang, Hui-Li Wang, et al. "S-allyl cysteine ameliorates heat stress-induced oxidative stress by activating Nrf2/HO-1 signaling pathway in BMECs." Toxicol Appl Pharmacol. 2021 Apr 1;416:115469. PMID: 33640343
- 254. Yu Wang , Wei Gao. "Effects of TNF-α on autophagy of rheumatoid arthritis fibroblast-like synoviocytes and regulation of the NF-κB signaling pathway." Immunobiology. 2021 Mar;226(2):152059. PMID: 33561598
Related Biological Data
Related Biological Data
Related Biological Data
Related Biological Data
Related Biological Data
Related Biological Data
Related Biological Data
Related Biological Data
| 100 tests | 1 mL x 1 |
| 500 tests | 5 mL x 1 |
| 1000 tests | 5 mL x 2 |
| 3000 tests | 5 mL x 6 |
| 10000 tests | 5 mL x 20 |
| Store at -20°C away from light. | |
More Sensitive than MTT, MTS, or WST-1
No Toxicity to Cell
Simpler Steps, No organic solvents required
Stable One Bottle Solution, ready-to-use
Advantages
