Toggle Nav

NAE

NAE (NEDD8-activating enzyme) catalyzes the initial step of the neddylation signaling that regulates CRLs (cullin-ring ubiquitin ligases) activities. Its downstream effect is linked to cancer cell growth and survival.

2 Items

per page
  1. MLN4924
    Catalog No. :
    B1036
    NAE inhibitor

    MLN4924 is a potent and selective inhibitor of NEDD8-activating enzyme (NAE) with IC50 value of 4nM .

  2. MLN4924 HCl salt
    Catalog No. :
    A3629
    NAE inhibitor
    MLN4924 is a potent and selective small molecule NEDD8-activating enzyme (NAE) inhibitor.

2 Items

per page