DNA Alkylating
DNA alkylating is the transfer of alkyl groups to particular bases, resulting in alkylation products such as O2‐alkylthymine and O6‐methylguanine that lead to DNA mutations.
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C4732 Illudin SSummary: potent antitumor sesquiterpene -
C4451 TrioxsalenSummary: intercalates into DNA and forms DNA single-strand adducts and interstrand crosslinks when activated with ultraviolet light -
B3742 Thio-TEPASummary: alkylating agent used to treat cancer -
B3489 CarmustineSummary: cell-cycle phase nonspecific alkylating antineoplastic agent -
B1399 TemozolomideSummary: DNA methylating, chemotherapeutic agent -
B1963 Lomustine1 CitationTarget: RNA synthesisSummary: Antineoplastic drug -
A8386 BusulfanSummary: DNA alkylating agent -
A2559 AltretamineSummary: Antineoplastic agent -
A3696 PalifosfamideSummary: Active metabolite of ifosfamide (IFOS)