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ROCK

ROCK (Rho-associated protein kinase) is a kinase belonging to the AGC family of serine-threonine kinases and takes part in regulating the shape and movement of cells by acting on the cytoskeleton.

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  1. Netarsudil (AR-13324)
    Catalog No. :
    B7807
    ROCK inhibitor
  2. LX7101 HCL
    Catalog No. :
    B5863
    Dual LIM-kinase and ROCK inhibitor
  3. GSK269962A
    Catalog No. :
    B3392
    ROCK inhibitor
    GSK269962A(GSK269962) is a potent ROCK inhibitor (IC50 values are 1.6 and 4 nM for recombinant human ROCK1 and ROCK2 respectively); displays greater than 30-fold selectivity for ROCK against a panel of serine/threonine kinases.
  4. SR-3677
    Catalog No. :
    B1294
    Rho Kinase (ROCK-II) inhibitor
    SR-3677 is a novel, potent and highly selective inhibitor of Rho Kinase (ROCK-II) with the IC50 value of ~0.3nM in enzyme and cell based assays .
  5. Y-27632
    Catalog No. :
    B1293
    ROCK inhibitor,potent and selective
    Y-27632 is a specific inhibitor of Rho-associated kinases(ROCK) family with Ki values of 0.22μM and 0.30μM for ROCK1 and ROCK2, respectively.
  6. Y-39983 dihydrochloride
    Catalog No. :
    B1176
    ROCK family inhibitor
    Y-39983 dihydrochloride is a novel and selective inhibitor of ROCK family with IC50 value of 3.6nM for ROCK .
  7. Fasudil (HA-1077) HCl
    Catalog No. :
    A5734
    Protein kinase inhibitor
    Cyclic nucleotide-dependent protein kinase inhibitor and Rho-associated kinase inhibitor (IC50 = 10.7 μM).
  8. GSK429286A
    Catalog No. :
    A5611
    Selective ROCK1/ROCK2 inhibitor
    Selective Rho-kinase inhibitor (IC50 values are 14, 780 and 1940 nM for ROCK1, RSK and p70S6K respectively).
  9. Thiazovivin
    Catalog No. :
    A5506
    ROCK inhibitor
    Greatly enhances the efficiency of fibroblast reprogramming to generate induced pluripotent stem cells (iPSCs) when used in combination with SB 431542 and PD 0325901.
  10. SLx-2119
    Catalog No. :
    A3825
    Selective ROCK2 inhibitor

    SLx-2119(KD-025) is a selective inhibitor of ROCK2 with IC50 of 105 nM [1].

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