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17,20-lyase

17,20-lyase, also known as CYP17A1, is a monooxygenase that catalyzes many reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids.

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  1. TAK-700 R-form
    Catalog No. :
    B1194
    17, 20-lyase inhibitor
    TAK-700 R-form is a highly selective inhibitor of 17, 20-lyase with IC50 value of 38nM .
  2. TAK-700 salt
    Catalog No. :
    A3852
    Androgen synthesis inhibitor
    TAK-700 salt
  3. Orteronel
    Catalog No. :
    A3686
    For castration-resistant prostate cancer, clinical candidate
    IC50: Orteronel inhibited monkey 17,20-lyase and 17-hydroxylase activities with IC50 values of 27 and 38 nmol/L, respectively

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