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ATP citrate lyase

ACLY (ATP citrate lyase) catalyzes the synthesis of acetyl-CoA from citrate. It is a cytosolic enzyme that involved in fetal growth/development, tumor cell growth/survival and metabolic disorder etc.

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  1. ETC-1002
    Catalog No. :
    A8710
    ACL inhibitor and AMPK activator
    ETC-1002 is an oral ACL inhibitor (IC50= 29 μM) and AMPK activator.
  2. BMS-303141
    Catalog No. :
    B1079
    ATP-citrate lyase inhibitor,potent
    BMS-303141 is a potent ATP-citrate lyase (ACL) inhibitor with IC50 value of 0.13 uM (human recombinant ACL).

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