ATP citrate lyase
ACLY (ATP citrate lyase) catalyzes the synthesis of acetyl-CoA from citrate. It is a cytosolic enzyme that involved in fetal growth/development, tumor cell growth/survival and metabolic disorder etc.
- ETC-1002Catalog No. :A8710ACL inhibitor and AMPK activatorETC-1002 is an oral ACL inhibitor (IC50= 29 μM) and AMPK activator.
- BMS-303141Catalog No. :B1079ATP-citrate lyase inhibitor,potentBMS-303141 is a potent ATP-citrate lyase (ACL) inhibitor with IC50 value of 0.13 uM (human recombinant ACL).