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Guanylate Cyclase

GC (guanylyl cyclaese) converts GTP into cGMP and pyrophosphate. sGC (soluble GC) is a nitric oxide receptor and pGC (transmembrance GC) is a natriiuritic peptide receptor. Its major functions include cell hyperplasia,hypertrophy, cell differentiation and tumor progression etc.

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  1. LY83583
    Catalog No. :
    C5613
    inhibitor of soluble guanylate cyclase and of cGMP production
  2. Ataciguat
    Catalog No. :
    C4216
    activator of the oxidized (heme-free) form of soluble guanylate cyclase (sGC)
  3. BAY 41-8543
    Catalog No. :
    C3639
    heme-dependent stimulator of soluble guanylate cyclase (sGC)
  4. Riociguat
    Catalog No. :
    A3767
    Soluble guanylate cyclase (sGC) stimulator

    Riociguat (BAY 63-2521; BAY 632521) is a novel drug that is currently in clinical development by Bayer. Riociguat (BAY 63-2521; BAY 632521) is a stimulator of soluble guanylate cyclase (sGC).

  5. Cinaciguat
    Catalog No. :
    A3314
    Soluble guanylate cyclase (sGC) activators
    Cinaciguat, also known as BAY-58-2667, is a NO-independent activator for sGC with EC50 of ∼10 nM for heme-free/oxidized sGC. [1]

5 Items

per page