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Guanylate Cyclase

GC (guanylyl cyclaese) converts GTP into cGMP and pyrophosphate. sGC (soluble GC) is a nitric oxide receptor and pGC (transmembrance GC) is a natriiuritic peptide receptor. Its major functions include cell hyperplasia,hypertrophy, cell differentiation and tumor progression etc.

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  1. BAY 41-8543
    C3639 BAY 41-8543
    Summary: heme-dependent stimulator of soluble guanylate cyclase (sGC)
      ≤3 mg/mL
  2. Ataciguat
    C4216 Ataciguat
    Summary: activator of the oxidized (heme-free) form of soluble guanylate cyclase (sGC)
      ≤1 mg/mL
  3. LY83583
    C5613 LY83583
    Summary: inhibitor of soluble guanylate cyclase and of cGMP production
      ≤3.8 mg/mL
  4. Cinaciguat
    A3314 Cinaciguat
    Target: guanylyl cyclase
    Summary: Soluble guanylate cyclase (sGC) activators
      Soluble in DMSO
  5. Riociguat
    A3767 Riociguat
    Summary: Soluble guanylate cyclase (sGC) stimulator
      insoluble in EtOH; insoluble in H2O; ≥16.95 mg/mL

5 Items

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