IκB/IKK
IKK (IκB kinase) is an enzyme complex that participates in NF-κB signaling pathway. It phosphorylates and inhibits IκB, thus leads to the activation of NF-κB. It is a target for treatment of inflammatory diseases and cancer.
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A4602 TPCA-12 CitationSummary: IKK-2 inhibitor,potent and selective -
B3033 Bay 11-70851 CitationSummary: NK-κB activation inhibitor -
B1585 SC-514Summary: ATP-competitive IKK-2 inhibitor, orally active -
B5756 ML 120B dihydrochlorideSummary: IKK2-selective inhibitor -
B4880 WS6Summary: inducer of β cell proliferation -
B4825 IKKε-IN-1Summary: potent IKKε inhibitor -
B4986 LY2409881Summary: potent and selective IKK2 inhibitor -
N1672 HonokiolSummary: Antioxidant/antitumor/antiangiogenic agent -
N1831 LuteolinTarget: AP-1|MMP|15-lipoxygenasesSummary: Antioxidant and free radical scavenger -
N1846 Tanshinone IIATarget: AP-1|MAGLSummary: Antioxidant and anti-inflammatory reagent