IκB/IKK
IKK (IκB kinase) is an enzyme complex that participates in NF-κB signaling pathway. It phosphorylates and inhibits IκB, thus leads to the activation of NF-κB. It is a target for treatment of inflammatory diseases and cancer.
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B5756 ML 120B dihydrochlorideSummary: IKK2-selective inhibitor -
B4880 WS6Summary: inducer of β cell proliferation -
B4825 IKKε-IN-1Summary: potent IKKε inhibitor -
B4986 LY2409881Summary: potent and selective IKK2 inhibitor -
B6089 PS-1145Summary: IKK inhibitor -
C4569 IKK-16 (hydrochloride)Summary: IκB kinases (IKKs) inhibitor -
B2028 Sodium salicylateSummary: NF-κB inhibitor -
B1587 IMD 03541 CitationSummary: IKKβ inhibitor -
B1643 Sodium 4-AminosalicylateSummary: NF-κB inhibitor -
A2604 CelastrolTarget: ProteasomeSummary: Antioxidant, anti-inflammatory and immunosuppressive agent