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CRM1

CRM1 (i.e. XPO-1, Exportin-1) is a mammalian ubiquitous protein that mediates the transport of protein and RNA across the nuclear membrane to the cytoplasm.

4 Items

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  1. Verdinexor (KPT-335)
    B4889 Verdinexor (KPT-335)
    Summary: XPO1/CRM1 inhibitor
      ≥44.2 mg/mL
  2. KPT-185
    B1462 KPT-185
    Summary: CRM1 inhibitor,selective and irrversible
      insoluble in H2O; ≥17.77 mg/mL
  3. KPT-330
    B1464 KPT-330
    Summary: CRM1 inhibitor, orally bioavailable and selective
  4. KPT-276
    B1463 KPT-276
    Target: nuclear export|CRM1
    Summary: inhibitor of nuclear export (SINE) and CRM1, orally bioavailable
      insoluble in EtOH; insoluble in H2O; ≥19.85 mg/mL

4 Items

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