Endopeptidases are peptidases that hydrolyze the peptide bonds in the nonterminal amino acids. They are separated into sub-types based on their catalytic mechanisms including metalloendopeptidases/neutral endopeptidase and lysyl endopeptidase etc.
- ThiorphanCatalog No. :C4349neprilysin inhibitor
- LHW090-A7Catalog No. :C4028neutral endopeptidase (NEP) inhibitor
- RacecadotrilCatalog No. :B1649Potent enkephalinase inhibitor
Racecadotril (acetorphan), a potent enkephalinase inhibitor (IC50= 4.5 uM), protects endogenous enkephalins from degradation.