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Endothelin Receptor

Endothelin receptors are members of rhodopsin-like g-protein coupled receptor (GPCRA) with 4 types (ETA, ETB1, ETB2 and ETC), which mediate various physiological processes including vasoconstriction, vasodilation, and neurotransmission etc.

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  1. Sarafotoxin S6a
    Catalog No. :
    B5217
    Endothelin receptor agonist
    New Product
  2. Sarafotoxin S6b
    Catalog No. :
    B5069
    non-selective endothelin receptor agonist
    New Product
  3. Endothelin 3 (human, rat)
    Catalog No. :
    B5062
    Endogenous neuropeptide with selectivity for the putative ETC endothelin receptor
    New Product
  4. Bosentan Hydrate
    Catalog No. :
    B1521
    endothelin receptor antagonist
    Bosentan is a competitive and dual antagonist of endothelin-1 at the endothelin-A (ET-A) and endothelin-B (ET-B) receptors.
  5. Bosentan
    Catalog No. :
    B1682
    Endothelin receptor antagonist
    Bosentan is a competitive and dual antagonist of endothelin-1 at the endothelin-A (ET-A) and endothelin-B (ET-B) receptors.
  6. Macitentan
    Catalog No. :
    A1929
    Endothelin (ET)(A) and ET(B) receptor antagonist

    Macitentan is an orally active, non-peptide dual endothelin (ET)(A) and ET(B) receptor antagonist for the potential treatment of idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH).

  7. Zibotentan (ZD4054)
    Catalog No. :
    A5489
    ETA receptor antagonist,potent and specific

    Zibotentan is a specific ETAR (Endothelian A receptor) antagonist with IC50 of 21 nM.

  8. Avosentan
    Catalog No. :
    A3208
    ETA receptor antagonist
    Avosentan(Ro 67-0565; SPP-301) is a potent, selective endothelin receptor(ETA receptor) antagonist.
  9. Atrasentan hydrochloride
    Catalog No. :
    A3201
    Endothelin receptor antagonist
    Atrasentan (A-147627) is an endothelin antagonist receptor (IC50=0.0551 nM, ETA) being developed for the treatment of prostate cancer.

9 Items

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