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XAO

XAO (xanthine oxidase), also known as xanthine oxidoreductase and xanthine dehydrogenase, catalyzes the oxidation of hypoxanthine to xanthine and the oxidation of xanthine to uric acid. It is an evolutionarily conserved enzymes that play a central role in purine catabolism.

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  1. Oxipurinol
    Catalog No. :
    C3548
    xanthine oxidoreductase inhibitor
  2. Topiroxostat
    Catalog No. :
    B1192
    Xanthine oxidoreductase (XOR) inhibitor
    Topiroxostat(FYX-051) is a novel and potent xanthine oxidoreductase (XOR) inhibitor with IC50 value of 5.3 nM.
  3. Allopurinol
    Catalog No. :
    A8360
    Xanthine oxidase inhibitor
    An anti-urolithic Xanthine oxidase inhibitor that decreases uric acid production and is used in treatment of hyperuricemia and chronic gout.
  4. Febuxostat
    Catalog No. :
    A5926
    non-purine selective inhibitor of xanthine oxidase
    IC50: Febuxostat displayed potent mixed-type inhibition of the activity of xanthine oxidase (XO), with Ki value of 0.6 nM [1].

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