XAO (xanthine oxidase), also known as xanthine oxidoreductase and xanthine dehydrogenase, catalyzes the oxidation of hypoxanthine to xanthine and the oxidation of xanthine to uric acid. It is an evolutionarily conserved enzymes that play a central role in purine catabolism.
- OxipurinolCatalog No. :C3548xanthine oxidoreductase inhibitor
- TopiroxostatCatalog No. :B1192Xanthine oxidoreductase (XOR) inhibitorTopiroxostat(FYX-051) is a novel and potent xanthine oxidoreductase (XOR) inhibitor with IC50 value of 5.3 nM.
- AllopurinolCatalog No. :A8360Xanthine oxidase inhibitorAn anti-urolithic Xanthine oxidase inhibitor that decreases uric acid production and is used in treatment of hyperuricemia and chronic gout.
- FebuxostatCatalog No. :A5926non-purine selective inhibitor of xanthine oxidaseIC50: Febuxostat displayed potent mixed-type inhibition of the activity of xanthine oxidase (XO), with Ki value of 0.6 nM .