5-Lipoxygenase
5-lipoxygenase catalyzes oxidation of AA at the 5-position to yield 5-HpETE and is a current target for pharmaceutical intervention in a number of diseases such as asthma, atherosclerosis and several cancers.
- A2486 MalotilateSummary: Stimulates hepatocyte regeneration
- A5384 ZileutonSummary: 5-lipoxygenase (5-LOX) inhibitor, orally active
- C3055 3-acetyl-11-keto-β-Boswellic AcidSummary: 5-lipoxygenase inhibitor
- C3091 11-keto-β-Boswellic AcidSummary: leukotriene synthesis inhibitor via 5-lipoxygenase
- C4696 Ebselen
- C3794 1-Naphthyl 3,5-dinitrobenzoateSummary: dual 5-lipoxygenase and microsomal prostaglandin E synthase-1 inhibitor
- C4199 HZ52Summary: 5-lipoxygenase inhibitor
- C4371 BW 755CSummary: dual inhibitor of 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways
- C4828 Piriprost (potassium salt)Summary: 5-lipoxygenase inhibitor
- B1207 Zileuton sodiumSummary: 5-lipoxygenase and leukotrienes inhibitor