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5-Lipoxygenase

5-lipoxygenase catalyzes oxidation of AA at the 5-position to yield 5-HpETE and is a current target for pharmaceutical intervention in a number of diseases such as asthma, atherosclerosis and several cancers.

Items 1-10 of 11

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  1. 3-acetyl-11-keto-β-Boswellic Acid
    C3055 3-acetyl-11-keto-β-Boswellic Acid
    Summary: 5-lipoxygenase inhibitor
  2. 11-keto-β-Boswellic Acid
    C3091 11-keto-β-Boswellic Acid
    Summary: leukotriene synthesis inhibitor via 5-lipoxygenase
      ≤5 mg/mL
  3. Ebselen
    C4696 Ebselen
  4. 1-Naphthyl 3,5-dinitrobenzoate
    C3794 1-Naphthyl 3,5-dinitrobenzoate
    Summary: dual 5-lipoxygenase and microsomal prostaglandin E synthase-1 inhibitor
      ≤0.1 mg/mL
  5. HZ52
    C4199 HZ52
    Summary: 5-lipoxygenase inhibitor
      ≤10 mg/mL
  6. BW 755C
    C4371 BW 755C
    Summary: dual inhibitor of 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways
      ≤30 mg/mL
  7. Piriprost (potassium salt)
    C4828 Piriprost (potassium salt)
    Summary: 5-lipoxygenase inhibitor
      ≤43 mg/mL
  8. Zileuton sodium
    B1207 Zileuton sodium
    Summary: 5-lipoxygenase and leukotrienes inhibitor
      Soluble in DMSO
  9. U-73122
    B3422 U-73122
     1 Citation
    Target: PC-PLC
    Summary: inhibitor of phospholipase C, phospholipase A2, and 5-LO (5-lipoxygenase)
  10. Malotilate
    A2486 Malotilate
    Summary: Stimulates hepatocyte regeneration
      insoluble in H2O; ≥14.419 mg/mL

Items 1-10 of 11

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