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Bcr-Abl

Bcl-Abl is a constitutively activated chimeric tyrosine kinase which is the genetic abnormality expressed in patient with CML (chronic myeloid leukemia).

Relate Categories
Category
  • ALK 21items
  • Ack1 1item
  • Axl 6items
  • BMX Kinase 1item
  • Bcr-Abl 20items
  • Broad Spectrum Protein Kinase Inhibitor 9items
  • CSF-1R 3items
  • DDR1/DDR2 Receptor 1item
  • EGFR 69items
  • EphB4 1item
  • FAK 10items
  • FGFR 17items
  • FLT3 19items
  • HER2 15items
  • IGF1R 9items
  • IRAK 6items
  • ITK 1item
  • Insulin Receptor 6items
  • LRRK2 9items
  • Lck 1item
  • PDGFR 24items
  • PTKs/RTKs 3items
  • Pyk2 3items
  • ROR 6items
  • Spleen Tyrosine Kinase (Syk) 12items
  • Src 24items
  • Tie-2 2items
  • Trk 12items
  • VEGFR 56items
  • c-FMS 2items
  • c-Kit 7items
  • c-MET 25items
  • c-RET 7items
Specificity
  1. Selective 5 items
Target
  1. FLT3 1 item
  2. VEGFR 1 item
  3. PDGFR 2 items
  4. c-Kit 1 item
  5. Bcr-Abl 8 items
  6. FGFR 1 item
  7. Src 4 items
  8. Tie-2 1 item
  9. KDR 1 item
  10. Abl kinases 1 item
Reported Experiments
  1. Animal Experiments 8 items
  2. Cell Experiments 7 items
Related Disease
  1. Acute Myeloid Leukemia 1 item
  2. Cancer 5 items
  3. Colon Cancer 1 item
  4. Leukemia 1 item
  5. Melanoma 1 item
  6. Prostate Cancer 1 item