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ALK

ALK (anaplastic lymphoma kinase) is a member of insulin receptor protein-tyrosine superfamily, functioning in embryonic development and involved in cell survival and cell fate.

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  1. PF-06463922
    B4882 PF-06463922
    Target: ALK|ROS1
    Summary: ALK/ROS1 inhibitor,potent and selective
      insoluble in H2O; ≥20.3 mg/mL
  2. LDN-214117
    B4842 LDN-214117
    Summary: potent and selective ALK2 inhibitor
      insoluble in H2O; ≥90 mg/mL
  3. Entrectinib
    B5859 Entrectinib
    Target: Trk Receptors|ALK|ROS1
    Summary: Orally active inhibitor of ALK kinase
      ≥28.05 mg/mL
  4. (R)-Crizotinib
    A3020 (R)-Crizotinib
     2 Citation
    Target: c-MET
    Summary: C-MET/ALK inhibitor,potent and ATP-competitve
      insoluble in H2O; insoluble in EtOH; ≥7.51 mg/mL
  5. ALK inhibitor 2
    A3155 ALK inhibitor 2
    Summary: ALK inhibitor, novel and selective
      Soluble in DMSO
  6. ASP3026
    A3193 ASP3026
    Summary: ALK inhibitor,potent and selective
      insoluble in H2O; ≥14.53 mg/mL
  7. CEP-28122
    C4025 CEP-28122
    Summary: anaplastic lymphoma kinase (ALK) inhibitor
      ≤30 mg/mL
  8. Crizotinib hydrochloride
    B3608 Crizotinib hydrochloride
    Summary: inhibitor of the c-Met kinase and the NPM-ALK
      ≥100.4 mg/mL
  9. DMH-1
    B3686 DMH-1
    Target: BMP and Other Activin Receptors
    Summary: Selective BMP ALK2 receptor
      insoluble in H2O; insoluble in EtOH; ≥9.51 mg/mL
  10. LDN-212854
    B3687 LDN-212854
    Summary: BMP receptor inhibitor,potent and selective
      insoluble in H2O; insoluble in EtOH; ≥20.3 mg/mL

Items 1-10 of 21

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