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Topoisomerase

Topoisomerase are enzymes that regulate the overwinding or underwinding of DNA.

Items 1-10 of 38

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  1. (S)-10-Hydroxycamptothecin
    B4745 (S)-10-Hydroxycamptothecin
    Target: Topoisomerases
    Summary: inhibitor of topoisomerase I
      ≥23.8 mg/mL
  2. Topotecan
    B4982 Topotecan
     1 Citation
    Summary: Topoisomerase 1 inhibitor
      ≥21.1 mg/mL
  3. Dp44mT
    B6021 Dp44mT
    Summary: iron chelator and anticancer agent
      ≥62.5 mg/mL
  4. 4'-Demethylepipodophyllotoxin
    A3123 4'-Demethylepipodophyllotoxin
    Summary: Anti-cancer drug
      ≥83.33 mg/mL
  5. Deferasirox Fe3+ chelate
    A3355 Deferasirox Fe3+ chelate
    Summary: Oral iron chelator
      Soluble in DMSO
  6. DOXO-EMCH
    A3372 DOXO-EMCH
    Summary: Prodrug of doxorubicin
      Soluble in DMSO
  7. Genz-644282
    A3434 Genz-644282
    Summary: Non-camptothecin inhibitor of topoisomerase I
      Soluble in DMSO
  8. Luotonin F
    C4228 Luotonin F
    Summary: stabilizing the DNA topoisomerase I-DNA complex
      ≤2.5 mg/mL
  9. Luotonin A
    C4433 Luotonin A
    Summary: binds to and stabilizes the topoisomerase I-DNA binary complex
      ≤3 mg/mL
  10. UK 1
    C5006 UK 1
    Summary: inhibitor of topoisomerase II and hepatitis C viral replication
      Soluble in DMSO;Soluble in dimethyl formamide

Items 1-10 of 38

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