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Topoisomerase

Topoisomerase are enzymes that regulate the overwinding or underwinding of DNA.

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  1. 9-amino Camptothecin
    Catalog No. :
    C5790
    topoisomerase I inhibitor
  2. UK 1
    Catalog No. :
    C5006
    inhibitor of topoisomerase II and hepatitis C viral replication
  3. Luotonin A
    Catalog No. :
    C4433
    binds to and stabilizes the topoisomerase I-DNA binary complex
  4. Luotonin F
    Catalog No. :
    C4228
    stabilizing the DNA topoisomerase I-DNA complex
  5. Dp44mT
    Catalog No. :
    B6021
    iron chelator and anticancer agent
  6. Topotecan
    Catalog No. :
    B4982
    Topoisomerase 1 inhibitor

    Topotecan (SKF104864) is an inhibitor of topoisomerase 1 and semisynthetic analogue of camptothecin [1].

  7. (S)-10-Hydroxycamptothecin
    Catalog No. :
    B4745
    inhibitor of topoisomerase I
    10-Hydroxycamptothecin is a DNA topoisomerase I inhibitor with potent anti-tumor activity.
  8. Ellipticine
    Catalog No. :
    B7382
    DNA topoisomerase II inhibitor
    New Product
  9. Pirarubicin
    Catalog No. :
    B2295
    Topoisomerase II inhibitor;anthracycline antibiotic

    Pirarubicin is an analogue of the anthracycline anti-neoplastic doxorubicin.

  10. Flumequine
    Catalog No. :
    B2292
    DNA topoisomerase II inhibitor,synthetic chemotherapeutic antibiotic
    Flumequine is a synthetic chemotherapeutic antibiotic, inhibiting topoisomerase II with IC50 of 15 μM.

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