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NKCC

NKCC (Na-K-Cl cotransporter) is an electrically silent membrane-bound channels that mediates Na and Cl reabsorption. It functions in regulating cell volume and ionic balance.

C4125 Ethacrynic Acid

Summary: A loop diuretic that inhibits the Na⁺/K⁺/2Cl^- cotransporter (NKCC2)

insoluble in H2O; ≥30.37 mg/mL
A1855 Bumetanide

Target: Na /K /Cl- Symporters (NKCCs)

Summary: NKCC cotransporter inhibitor

insoluble in H2O; ≥36.37 mg/mL
A8435 Furosemide

Target: Na /K /Cl- Symporters (NKCCs)|GABAA Receptors

Summary: GABAA receptors antagonist