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EGFR

EGFR (epidermal growth factor receptor) is the cell-surface receptor of its specific ligands, including epidermal growth factor and TGFα (transforming growth factor α) and is a receptor tyrosine kinase.

Relate Categories
Category
  • ALK 21items
  • Ack1 1item
  • Axl 6items
  • BMX Kinase 1item
  • Bcr-Abl 20items
  • Broad Spectrum Protein Kinase Inhibitor 9items
  • CSF-1R 3items
  • DDR1/DDR2 Receptor 1item
  • EGFR 69items
  • EphB4 1item
  • FAK 10items
  • FGFR 17items
  • FLT3 19items
  • HER2 15items
  • IGF1R 10items
  • IRAK 6items
  • ITK 1item
  • Insulin Receptor 6items
  • LRRK2 9items
  • Lck 1item
  • PDGFR 24items
  • PTKs/RTKs 3items
  • Pyk2 3items
  • ROR 6items
  • Spleen Tyrosine Kinase (Syk) 12items
  • Src 23items
  • Tie-2 2items
  • Trk 12items
  • VEGFR 56items
  • c-FMS 2items
  • c-Kit 7items
  • c-MET 25items
  • c-RET 7items
Specificity
  1. Selective 14 items
Reversibility
  1. Reversible 2 items
  2. Irreversible 7 items
Target
  1. Histone Deacetylases (HDACs) 1 item
  2. VEGFR 1 item
  3. PDGFR 2 items
  4. Bcr-Abl 1 item
  5. FGFR 2 items
  6. Src 2 items
  7. STAT 1 item
  8. EGFR 19 items
  9. JAK 1 item
  10. ErbB 4 items
  11. c-MET 1 item
  12. PKC 1 item
  13. HER2 1 item
  14. Angiotensin-Converting Enzymes (ACEs) 1 item
  15. 5-Lipoxygenases 1 item
  16. Insulin Receptors 1 item
  17. IRG-1R 1 item
  18. insulin 1 item
  19. ErbB-2 1 item
  20. PTK 1 item
  21. enoyl-acyl-carrier protein reductase 1 item
Reported Experiments
  1. Animal Experiments 21 items
  2. Cell Experiments 18 items
Related Disease
  1. Bladder Cancer 2 items
  2. Breast Cancer 7 items
  3. Cancer 18 items
  4. Colon Cancer 1 item
  5. Colorectal Cancer 2 items
  6. Glioblastoma 2 items
  7. Leukemia 1 item
  8. Liver Cancer 1 item
  9. Non-small Cell Lung Cancer 3 items
  10. Ovarian Cancer 1 item
  11. Pancreatic Cancer 2 items
  12. Prostate Cancer 2 items