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EGFR

EGFR (epidermal growth factor receptor) is the cell-surface receptor of its specific ligands, including epidermal growth factor and TGFα (transforming growth factor α) and is a receptor tyrosine kinase.

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  1. HKI 357
    B5456 HKI 357
    Summary: irreversible inhibitor of ErbB2 (HER2) and EGFR
      Soluble in DMSO
  2. WZ3146
    A8881 WZ3146
    Summary: Mutant EGFR inhibitor, potent and irreversible
      ≥23.25 mg/mL
  3. FIIN-2
    A8696 FIIN-2
    Target: FGFR
    Summary: Irreversible inhibitor of FGFR
      ≥31.75 mg/mL
  4. EGF816
    B5889 EGF816
     2 Citation
    Target: EGFR
    Summary: Novel covalent inhibitor of mutant-selective EGFR
      Soluble in DMSO
  5. CL-387785 (EKI-785)
    B5899 CL-387785 (EKI-785)
    Summary: Irreversible inhibiter of EGFR
      insoluble in EtOH; insoluble in H2O; ≥16.85 mg/mL
  6. EAI045
    B6054 EAI045
    Summary: Inhibitor of L858R/T790M EGFR mutants
      ≥38.3 mg/mL
  7. Olmutinib (HM61713, BI 1482694)
    B7813 Olmutinib (HM61713, BI 1482694)
    Summary: EGFR mutant-specific inhibitor
  8. NSC228155
    B7815 NSC228155
    Summary: EGFR activator
      ≥29 mg/mL
  9. EGFR/ErbB2 Inhibitor
    C3285 EGFR/ErbB2 Inhibitor
    Summary: EGFR and c-ErbB2 inhibitor
      ≤1 mg/mL
  10. EGFR Inhibitor
    C3327 EGFR Inhibitor
    Summary: EGFR inhibitor
      insoluble in H2O; insoluble in EtOH; ≥60.7 mg/mL

Items 1-10 of 69

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