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Anti-LGR5 & EGFR Antibody (Petosemtamab)

Catalog No.
F1411
Anti-LGR5 & EGFR Antibody (Petosemtamab)
Grouped product items
SizePriceStock Qty
100ug
Please inquire
Ship with 3-5 days
1mg
Please inquire
Ship with 3-5 days
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Petosemtamab (MCLA 158) is an anti-EGFR (Kd : 0.22 nM) and antiLGR5 (Kd 0.86 nM) monoclonal antibody (mAb). Petosemtamab leads toEGFR Signal transduction blockade and receptor degradation. Petosemtamab can be used in the study of solid tumors such as head and neck squamous cell carcinoma (HNSCC) and metastatic colorectal cancer (CRC).

Quality Control

Quality Control & DataSheet

View current batch:
 

M.Wt

145.97 kDa

Shipping

Dry ice

Cas No.

2213450-26-9

Storage

-80°C

Expiration Date

2 years

Form

Liquid

Concentration

See label

Reconstitution

For reconstitution, we recommend adding sterile, distilled water to achieve a final antibody concentration. Gently shake it to solubilize the protein completely. Do not vortex.

Host

CHO

Alternative Names

MCLA-158, MCLA158

Buffer System

100 mM Pro 20 mM Arg pH 5.0. No preservative!

Target Accession

P00533 & O75473

Reactivity

Human

Conjugation

Unconjugated

Clonality

Monoclonal

Isotype

IgG1

Application

ELISA, FACS, Kinetics, Functional assay, Animal Model

Target

LGR5 & EGFR

Note

Please avoid freeze-thaw cycles.