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MEK1/2

MEK1/2, also known as MAPKK (mitogen-activated protein kinase kinase), is a kinase enzyme which phosphorylates MAPK (mitogen-activated protein kinase).

Items 1-10 of 37

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  1. AZD6244 (Selumetinib)
    A8207 AZD6244 (Selumetinib)
     3 Citation
    Summary: MEK inhibitor
      ≥22.88 mg/mL
  2. PD98059
    A1663 PD98059
     9 Citation
    Target: MEK
    Summary: MEK inhibitor,selective and reversible
      insoluble in EtOH; insoluble in H2O; ≥40.23 mg/mL
  3. SL-327
    A1894 SL-327
     1 Citation
    Target: MEK
    Summary: Selective MEK1/2 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥16.75 mg/mL
  4. PD184352 (CI-1040)
    A1792 PD184352 (CI-1040)
    Target: MEK
    Summary: Selective MEK inhibitor
      ≥47.9 mg/mL
  5. U0126-EtOH
    A1337 U0126-EtOH
     10 Citation
    Target: MEK
    Summary: MEK1/2 inhibitor
      ≥21.33 mg/mL
  6. Pimasertib (AS-703026)
    A5573 Pimasertib (AS-703026)
    Target: MEK
    Summary: MEK1/2 inhibitor
      ≥21.55 mg/mL
  7. PD318088
    A5707 PD318088
    Target: MEK
    Summary: Allosteric MEK1/2 inhibitor, non-ATP competitive
      ≥28.05 mg/mL
  8. BIX 02189
    A5801 BIX 02189
    Target: MEK|ERK
    Summary: Selective MEK5 inhibitor
      ≥22.05 mg/mL
  9. BIX 02188
    A5803 BIX 02188
    Target: MEK
    Summary: MEK5 inhibitor,potent and selective
      insoluble in H2O; insoluble in EtOH; ≥10.3 mg/mL
  10. MEK162 (ARRY-162, ARRY-438162)
    A1947 MEK162 (ARRY-162, ARRY-438162)
    Target: MEK
    Summary: MEK1/2 inhibitor,potent and selective
      insoluble in H2O; insoluble in EtOH; insoluble in DMSO

Items 1-10 of 37

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