EWS-FLI1 is a transcription factor specific to the Ewing’s sarcoma. EWS-FL1I coupling to RHA (RNA helicase A) is essential for its oncogenic function.
- RK-33Catalog No. :B7810DDX3 (a RNA helicase) inhibitor
- YK-4-279Catalog No. :A3946RNA Helicase A (RHA) inhibitorYK 4-279 is an inhibitor of RNA Helicase A (RHA) binding to the oncogenic transciption factor EWS-FLI1. YK-4-279 inhibits Ewing's sarcoma family tumor (ESFT) cell growth; YK-4-279 induces apoptosis.