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Autophagy

Autophagy is a catabolic process which degrades and recycles long-lived proteins and cytoplasmic organelles through lysosome. It plays an important role in growth regulation and maintenance of homeostasis.

Items 1-10 of 33

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  1. VPS34-IN1
    VPS34-IN1
    Catalog No. :
    B6179
    Vps34 inhibitor
  2. MRT68921
    MRT68921
    Catalog No. :
    B6174
    dual autophagy kinase ULK1/2 inhibitor
  3. PIK-III
    PIK-III
    Catalog No. :
    B6160
    VPS34 inhibitor and inhibits autophagy
  4. Spautin-1
    Spautin-1
    Catalog No. :
    B5873
    Novel autophagy inhibitor
  5. SBI-0206965
    SBI-0206965
    Catalog No. :
    A8715
    ULK1 inhibitor
  6. LY3009120
    LY3009120
    Catalog No. :
    A8716
    pan-RAF and RAF dimer inhibitor
  7. SAR405
    SAR405
    Catalog No. :
    A8883
    Selective ATP-competitive inhibitor of Vps34

    SAR405 is a selective ATP-competitive inhibitor of Vps34 with a Kd value of 1.5 nM.

  8. KC01
    KC01
    Catalog No. :
    A8884
    A selective inhibitor of ABHD16A
    KC01 is a potent and selective inhibitor of ABHD16A. By measuring competitive gel-based ABPP, the IC50 values of inhibition of ABHD16A by KC01 and KC02 were ~0.2–0.5 μM and >10 μM, respectively.
  9. SMER 28
    SMER 28
    Catalog No. :
    B7637
    Positive regulator of autophagy
    New Product
  10. Divalproex Sodium
    Divalproex Sodium
    Catalog No. :
    B1391
    Epilepsy/migraines/bipolar disorder medicine

    Divalproex sodium (USAN) consists of a compound of sodium valproate and valproic acid in a 1:1 molar relationship in an enteric coated form.

Items 1-10 of 33

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Relate Categories
Category
  • Autophagy 33items
  • DUB 17items
  • E1 Activating 1item
  • E2 conjugating 1item
  • E3 Ligase 4items
  • Proteasome 24items
  • p97 6items
Specificity
  1. Selective 14 items
Reversibility
  1. Reversible 3 items
  2. Irreversible 2 items
Target
  1. Cathepsins 1 item
  2. Histone Deacetylases (HDACs) 1 item
  3. PI3K 2 items
  4. Raf 1 item
  5. ULK1 1 item
  6. Deubiquitinating enzymes (DUBs) 1 item
  7. Microtubules/Tubulins 2 items
  8. Renin 1 item
  9. HIV proteases 1 item
  10. Pepsins 1 item
  11. Vacuolar-type ATPase 1 item
  12. Autophagy 3 items
  13. interleukin receptor 1 item
  14. NMPRTase 1 item
  15. P97 ATPase 1 item
Reported Experiments
  1. Animal Experiments 12 items
  2. Cell Experiments 9 items
Related Disease
  1. Breast Cancer 4 items
  2. Cancer 14 items
  3. Colon Cancer 1 item
  4. Colorectal Cancer 2 items
  5. Glioblastoma 1 item
  6. Lung Cancer 2 items
  7. Multiple Myeloma 2 items
  8. Ovarian Cancer 2 items
  9. Prostate Cancer 1 item
  10. Renal Cell Carcinoma 1 item