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EZH2

EZH2 (enhancer of zeste homolog 2) is a polycomb group protein and histone methyltrasferase that associated with transcriptional repression. It catalyzes trimethylation of H3K27me3 (histone H3 lysine 27) as a catalytic subunit of PRC2 (polycomb repressive complex 2).

8 Items

per page
  1. GSK503
    B5833 GSK503
     2 Citation
    Summary: EZH2 inhibitor
      ≥21.65 mg/mL
  2. EI1
    B1021 EI1
    Summary: EZH2 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥19.5 mg/mL
  3. 3-Deazaneplanocin A (DZNep) hydrochloride
    A8182 3-Deazaneplanocin A (DZNep) hydrochloride
     1 Citation
    Target: EZH2
    Summary: SAHH and EZH2 inhibitor
      insoluble in EtOH; ≥14.94 mg/mL
  4. CPI-169
    B4678 CPI-169
     1 Citation
    Target: EZH2|EZH1
    Summary: EZH2 inhibitor
      ≥26.45 mg/mL
  5. EPZ005687
    A4171 EPZ005687
     2 Citation
    Target: EZH2
    Summary: EZH2 inhibitor,potent and selective
      insoluble in EtOH; insoluble in H2O; ≥3.86 mg/mL
  6. 3-Deazaneplanocin,DZNep
    A1905 3-Deazaneplanocin,DZNep
     6 Citation
    Target: Hydrolase
    Summary: S-adenosylhomocysteine and EZH2 inhibitor
      insoluble in EtOH; ≥17.07 mg/mL
  7. GSK126
    A3446 GSK126
     5 Citation
    Target: EZH2
    Summary: EZH2 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥4.38 mg/mL
  8. GSK343
    A3449 GSK343
     1 Citation
    Target: EZH2
    Summary: EZH2 inhibitor,potent,selective and cell permeable

8 Items

per page