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SGLT

SGLT (sodium-glucose linked transporter) uses the energy from the downhill sodium ion gradient created by the ATPase pump to transport glucose across the apical membrane against an uphill glucose gradient.

7 Items

per page
  1. Empagliflozin (BI 10773)
    A4601 Empagliflozin (BI 10773)
     2 Citation
    Summary: SGLT-2 inhibitor for oral treatment of type 2 diabetes
      insoluble in H2O; ≥20.75 mg/mL
  2. Dapagliflozin
    A5854 Dapagliflozin
    Summary: SGLT2 inhibitor,potent and selective
  3. Canagliflozin
    A8333 Canagliflozin
     1 Citation
    Target: SGLT
    Summary: SGLT2 inhibitor,potent and selective
      ≥22.25 mg/mL
  4. fluoro-Dapagliflozin
    C5119 fluoro-Dapagliflozin
    Summary: selective sodium-glucose cotransporter (SGLT) inhibitor
      ≤30 mg/mL
  5. galacto-Dapagliflozin
    C5221 galacto-Dapagliflozin
    Summary: potent inhibitor of human SGLT2
      ≤30 mg/mL
  6. LX-4211
    A3567 LX-4211
    Summary: SGLT1/SGLT2 inhibitor
  7. PF-04971729
    A3715 PF-04971729
    Summary: SGLT inhibitor
      Soluble in DMSO

7 Items

per page
Relate Categories
Specificity
  1. Selective1 item
Target
  1. SGLT1 item
Reported Experiments
  1. Animal Experiments1 item
Related Disease
  1. Type 2 Diabetes1 item