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CYP3A/CYP450

CYP3A4 is an enzyme of cytochrome P450 superfamily found in human liver. It catalyzes the metabolism of endogenous and exogenous agents ( e.g. xenobiotics).

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  1. YM 511
    B5405 YM 511
    Summary: aromatase (CYP19) inhibitor
      <35.42 mg/mL
  2. 7-Ethoxyresorufin
    B5963 7-Ethoxyresorufin
    Target: Cytochrome P450 (CYP450)
    Summary: Specific subtrate of CYP1A
      Soluble in DMSO
  3. Diosmetin
    B5990 Diosmetin
    Summary: CYP1A1 inhibitor
      insoluble in H2O; ≥13.65 mg/mL
  4. ABT
    B7737 ABT
    Summary: Cytochrome P450 inhibitor
      ≥12.93 mg/mL
  5. Methoxyresorufin
    B5723 Methoxyresorufin
    Summary: fluorometric substrate of cytochrome P450
      insoluble in DMSO
  6. Pentoxyresorufin
    B5724 Pentoxyresorufin
    Summary: fluorometric cytochrome P450 substrate
      insoluble in ethanol;insoluble in DMSO
  7. TMS
    B6768 TMS
    Summary: cytochrome P450 1B1 inhibitor
      Soluble in DMSO
  8. 3-Cyano-7-ethoxycoumarin
    B7714 3-Cyano-7-ethoxycoumarin
    Summary: Fluorescent P450 substrate
      Soluble in DMSO
  9. Cobicistat (GS-9350)
    A4313 Cobicistat (GS-9350)
    Target: Cytochrome P450 (CYP450)
    Summary: Selective CYP3A inhibitor
      insoluble in H2O; ≥150.9 mg/mL
  10. Voriconazole
    A4320 Voriconazole
    Summary: CYP51 inhibitor
      ≥34.9 mg/mL

Items 1-10 of 17

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