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TLR

TLR (Toll-like receptor) is a family of receptors that expressed on immune cells including B lymphoctes, macrophages and mast cells. Ir identifies pathogen-associated molecular patterns and mediate the cytokines productions for activation of innate immunity.

Items 1-10 of 12

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  1. Resiquimod (R-848)
    B1054 Resiquimod (R-848)
     2 Citation
    Target: Toll-like receptors (TLRs)
    Summary: Immune response modifier
  2. Poly(I:C)
    B5551 Poly(I:C)
    Target: Toll-like receptors (TLRs)
    Summary: Toll-like receptor 3 (TLR3) agonist
      insoluble in DMSO; insoluble in EtOH; ≥21.5 mg/mL
  3. CU CPT 4a
    B5752 CU CPT 4a
    Summary: TLR3 inhibitor
      <37.78 mg/mL
  4. CU CPT 22
    B5753 CU CPT 22
    Summary: toll-like receptor 1/2 (TLR1/2) inhibitor
      ≥33.5 mg/mL
  5. Pam2CSK4
    B5665 Pam2CSK4
    Summary: toll-like receptor 2/6 (TLR2/6) agonist
  6. RWJ 21757
    B7159 RWJ 21757
    Summary: Toll-like receptor 7 (TLR7) agonist
      Soluble in DMSO
  7. Imiquimod hydrochloride
    B1186 Imiquimod hydrochloride
    Summary: Toll-like receptor 7 agonist
  8. Imiquimod maleate
    B1187 Imiquimod maleate
    Summary: Immune response modifier
      Soluble in DMSO
  9. Suprofen
    B2133 Suprofen
    Target: COX
    Summary: dual COX-1/COX-2 inhibitor
      insoluble in H2O; ≥82.8 mg/mL
  10. TAK-242
    A3850 TAK-242
     7 Citation
    Target: Toll-like receptors (TLRs)|NO Donors / Precursors|IL Receptors
    Summary: TLR4 inhibitor

Items 1-10 of 12

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