PDE
PDE (phosphodiesterases) catalyze the hydrolysis of cGMP and/or cAMP. Stimulus such as light, neurotransmitter and hormone trigger PDE to regulate various biological response including vascular smooth muscle proliferation/contraction, hormone secretion and plate aggregation etc.
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Summary: inhibitor of PDE4 -
Summary: cAMP derivative used to bind PDE10 GAF domain -
Summary: PDE4 inhibitor -
Summary: phosphodiesterase 7 (PDE7) inhibitor -
Summary: selective inhibitor of PDE4 -
Summary: cGMP-specific phosphodiesterase PDE V inhibitor -
Summary: analog of tadalafil, a potent inhibitor of phosphodiesterase 5 -
Summary: PDE5 inhibitor -
Summary: PDE10A inhibitor -
Summary: PDE4 inhibitor