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FLT3

FLT3 (FMS-like tyrosine kinase 3) is a cytokine receptor which belongs to the receptor tyrosine kinase class III and plays a role in cell survival, proliferation, and differentiation.

Items 1-10 of 19

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  1. 5'-Fluoroindirubinoxime
    B5516 5'-Fluoroindirubinoxime
    Summary: FMS-like receptor tyrosine kinase-3 (FLT3) inhibitor
      <29.53 mg/mL
  2. G-749
    A8889 G-749
    Target: Aurora Kinases|FLT3|c-RET
    Summary: FLT3 inhibitor
      ≥26.05 mg/mL
  3. UNC2025
    B8016 UNC2025
     1 Citation
    Target: MER|FLT3
    Summary: orally bioavailable dual MER/FLT3 inhibitor
      ≥23.85 mg/mL
  4. TG101209
    A4145 TG101209
    Summary: JAK2/3 inhibitor
      ≥25.5 mg/mL
  5. KW 2449
    A4123 KW 2449
    Target: Aurora Kinases|FLT3|Bcr-Abl
    Summary: Multikinase inhibitor
      insoluble in EtOH; insoluble in H2O; ≥16.6 mg/mL
  6. Amuvatinib (MP-470, HPK 56)
    A4237 Amuvatinib (MP-470, HPK 56)
    Summary: Tyrosine kinase inhibitor
      ≥22.4 mg/mL
  7. AST 487
    A3194 AST 487
     1 Citation
    Target: RET
    Summary: RET kinase inhibitor
      ≥26.5 mg/mL
  8. SU5614
    B6097 SU5614
    Summary: tyrosine kinase inhibitor
      ≥27.3 mg/mL
  9. Tandutinib (MLN518) HCl
    B7853 Tandutinib (MLN518) HCl
    Summary: FLT3 inhibitor,potent and selective
      ≥59.9 mg/mL
  10. SB1317
    A3794 SB1317
    Summary: CDK,JAK and FLT inhibitor
      insoluble in H2O; ≥44.87 mg/mL

Items 1-10 of 19

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