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FLT3

FLT3 (FMS-like tyrosine kinase 3) is a cytokine receptor which belongs to the receptor tyrosine kinase class III and plays a role in cell survival, proliferation, and differentiation.

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  1. Tandutinib (MLN518) HCl
    Catalog No. :
    B7853
    FLT3 inhibitor,potent and selective
  2. SU5614
    Catalog No. :
    B6097
    tyrosine kinase inhibitor
  3. UNC2025
    Catalog No. :
    B8016
    orally bioavailable dual MER/FLT3 inhibitor

    UNC2025 is a potent and orally bioavailable Mer/Flt3 dual inhibitor with IC50 of 0.8/0.74 nM for Mer/Flt3.

  4. G-749
    Catalog No. :
    A8889
    FLT3 inhibitor
    G-749 is a selective inhibitor of Fms-like tyrosine receptor kinase-3 (FLT3) with IC50 value of 0.4 nM for wild-type FLT3.
  5. 5'-Fluoroindirubinoxime
    Catalog No. :
    B5516
    FMS-like receptor tyrosine kinase-3 (FLT3) inhibitor
    New Product
  6. Tandutinib (MLN518)
    Catalog No. :
    B1526
    FLT3 inhibitor,potent and selective
    Tandutinib (MLN518, CT53518) is a novel, selective and small-molecule inhibitor of FLT3 with IC50 value of 0.22μM .
  7. TCS 359
    Catalog No. :
    A2323
    Potent FLT3 inhibitor
    Cluster of differentiation antigen 135 (CD135) also known as Fms-like tyrosine kinase 3 (FLT-3), is a protein that in humans is encoded by the FLT3 gene.
  8. Quizartinib (AC220)
    Catalog No. :
    A5793
    FLT3 inhibitor,potent and selective
    Quizartinib (AC220) is a 2nd-generation FLT3 inhibitor for Flt3(ITD/WT) with IC50 value of 1.1 nM/4.2 nM, and it is ten-fold more selective for Flt3 than PDGFRα, PDGFRβ, KIT, RET and CSF-1R [1].
  9. Ponatinib (AP24534)
    Catalog No. :
    A5467
    pan-BCR-ABL inhibitor,multi-kinase inhibitor
    Potent multi-kinase and pan-BCR-ABL inhibitor.
  10. Cabozantinib (XL184, BMS-907351)
    Catalog No. :
    A2977
    VEGFR2/Met/Ret/Kit/FLT//AXL inhibitor
    XL184 (Cabozantinib) is a potent VEGFR2 inhibitor with IC50 of 0.035 nM.

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