FLT3 (FMS-like tyrosine kinase 3) is a cytokine receptor which belongs to the receptor tyrosine kinase class III and plays a role in cell survival, proliferation, and differentiation.
- Tandutinib (MLN518) HClCatalog No. :B7853FLT3 inhibitor,potent and selective
- SU5614Catalog No. :B6097tyrosine kinase inhibitor
- UNC2025Catalog No. :B8016orally bioavailable dual MER/FLT3 inhibitor
UNC2025 is a potent and orally bioavailable Mer/Flt3 dual inhibitor with IC50 of 0.8/0.74 nM for Mer/Flt3.
- G-749Catalog No. :A8889FLT3 inhibitorG-749 is a selective inhibitor of Fms-like tyrosine receptor kinase-3 (FLT3) with IC50 value of 0.4 nM for wild-type FLT3.
- 5'-FluoroindirubinoximeCatalog No. :B5516FMS-like receptor tyrosine kinase-3 (FLT3) inhibitorNew Product
- Tandutinib (MLN518)Catalog No. :B1526FLT3 inhibitor,potent and selectiveTandutinib (MLN518, CT53518) is a novel, selective and small-molecule inhibitor of FLT3 with IC50 value of 0.22μM .
- TCS 359Catalog No. :A2323Potent FLT3 inhibitorCluster of differentiation antigen 135 (CD135) also known as Fms-like tyrosine kinase 3 (FLT-3), is a protein that in humans is encoded by the FLT3 gene.
- Quizartinib (AC220)Catalog No. :A5793FLT3 inhibitor,potent and selectiveQuizartinib (AC220) is a 2nd-generation FLT3 inhibitor for Flt3(ITD/WT) with IC50 value of 1.1 nM/4.2 nM, and it is ten-fold more selective for Flt3 than PDGFRα, PDGFRβ, KIT, RET and CSF-1R .
- Ponatinib (AP24534)Catalog No. :A5467pan-BCR-ABL inhibitor,multi-kinase inhibitorPotent multi-kinase and pan-BCR-ABL inhibitor.
- Cabozantinib (XL184, BMS-907351)Catalog No. :A2977VEGFR2/Met/Ret/Kit/FLT//AXL inhibitorXL184 (Cabozantinib) is a potent VEGFR2 inhibitor with IC50 of 0.035 nM.