MNS
Catalog No.
A8661
Inhibitor of Src/Syk tyrosine kinases
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Selective inhibitor of Src and Syk tyrosine kinases. Displays antiaggregative activity via inhibition of GPIIb/IIIa activation (IC50 = 12.7 μM for thrombin-induced platelet aggregation). Exhibits no effects on Ca2+-dependent enzymes, PKC or arachidonic ac
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 193.16 |
| Cas No. | 1485-00-3 |
| Formula | C9H7NO4 |
| Solubility | insoluble in H2O; ≥2.98 mg/mL in EtOH with gentle warming and ultrasonic; ≥8 mg/mL in DMSO |
| Chemical Name | 5-[(E)-2-nitroethenyl]-1,3-benzodioxole |
| SDF | Download SDF |
| Canonical SMILES | [O-][N+](C=Cc(cc1)cc2c1OCO2)=O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
| Description | MNS is an inhibitor of tyrosine kinases with IC50 values of 2.5 μM, 29.3 μM and 1.7 μM for Syk, Src and p97, respectively. | |||||
| Targets | p97 | Syk | Src | |||
| IC50 | 1.7 μM | 2.5 μM | 29.3 μM | |||
Quality Control & MSDS
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Chemical structure
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