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Potassium Channel

Potassium channels are voltage-gated ion channels that selectively permeate potassium ion through the excitable membrane. It regulates the release of neurotransmitters, insulin secretion, smooth muscle contraction and heart rate etc.

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  1. TRAM-34
    A1888 TRAM-34
    Target: Calcium-Activated Potassium (KCa) Channels
    Summary: KCa3.1 blocker,potent and highly selective
      insoluble in H2O; insoluble in EtOH; ≥17.25 mg/mL
  2. Repaglinide
    A5316 Repaglinide
    Summary: Kir6 (KATP) channel blocker
  3. Glipizide
    A8438 Glipizide
    Summary: Oral anti-diabetic medication
      insoluble in H2O; ≥16.8 mg/mL
  4. Dofetilide
    A8417 Dofetilide
     2 Citation
    Target: Delayed rectifier outward potassium current (IKr)
    Summary: Potassium channel inhibitor
      ≥21.15 mg/mL
  5. VU 591 hydrochloride
    B5539 VU 591 hydrochloride
    Summary: renal outer medullary potassium channel (Kir1.1, ROMK) antagonist
      <36.83 mg/mL
  6. NS 3623
    B5605 NS 3623
    Summary: human ether-a-go-go (hERG) KV11.1 potassium channel activator
      <42.72 mg/mL
  7. ML 213
    B5628 ML 213
    Summary: KV7.2 (KCNQ2) and KV7.4 (KCNQ4) channel opener
      Soluble in DMSO
  8. NS 11021
    B5715 NS 11021
    Summary: large-conductance Ca2+-activated potassium channels activator
      Soluble in DMSO
  9. NS 6180
    B5740 NS 6180
    Summary: KCa3.1 channel blocker
      Soluble in DMSO
  10. Azimilide
    B4849 Azimilide
    Summary: class III anti-arrhythmic drug
      insoluble in EtOH; insoluble in DMSO; ≥4.18 mg/mL

Items 1-10 of 76

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