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GPR109A

GPR109A (also known as hydroxycarboxylic acid receptor 2) is a nicotinic acid/niacin and (D)-beta-hydroxybutyrate receptor. It conveys acid-induced apoptosis in matureneutrophils and may lead to neutrophilapoptosis after niacin activation.

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 Paper Citing APExBIO Products  Ongoing Clinical Trials  Solubility in DMSO  Solubility in Water  Solubility in Ethanol  Solubility in Dimethyl Formamide
  1. PF-05212384 (PKI-587)
    B2179 PF-05212384 (PKI-587)
    Summary: PI3Kα, PI3Kγ and mTOR inhibitor
      ≥15.4 mg/mL
  2. MK-6892
    A3623 MK-6892
    Summary: Highly potential GPR109A agonist
      soluble in dmso

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