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Rho

Rho GTPases act as molecular switches that convert and amplify external signals into cellular effects upon activation of cell surface receptor in various signaling transduction pathway. It functions in cell proliferation, motility, survival cytoskeletal remodeling and membrane trafficking etc.

Items 1-10 of 12

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  1. K-Ras(G12C) inhibitor 6
    B3694 K-Ras(G12C) inhibitor 6
    Target: KRAS G12C
    Summary: K-Ras (G12C) inhibitor
      insoluble in H2O; insoluble in EtOH; ≥20.25 mg/mL
  2. Zoledronic Acid
    A1352 Zoledronic Acid
    Target: Farnesyl Diphosphate Synthases
    Summary: Potent nitrogen-containing bisphosphonates
      insoluble in DMSO; insoluble in H2O; insoluble in EtOH
  3. NSC23766 trihydrochloride
    A1952 NSC23766 trihydrochloride
    Summary: Selective inhibitor of Rac1-GEF interaction.
      ≥26.55 mg/mL
  4. ZCL278
    A8300 ZCL278
     1 Citation
    Target: Cdc42
    Summary: Selective Cdc42 inhibitor
      ≥29.25 mg/mL
  5. CCG-100602
    C3687 CCG-100602
     1 Citation
    Summary: Rho pathway inhibitor
      ≥152.4 mg/mL
  6. SB 772077B dihydrochloride
    B5529 SB 772077B dihydrochloride
    Summary: Rho-kinase (ROCK) inhibitor
      <41.53 mg/mL
  7. AS 1892802
    B5773 AS 1892802
    Summary: ROCK inhibitor,potent and ATP-competitive
      Soluble in DMSO
  8. 6H05
    A8902 6H05
    Summary: K-Ras inhibitor
      ≥29.5 mg/mL
  9. K-115
    B4809 K-115
    Summary: Selective Rho kinase inhibitor
      insoluble in EtOH; ≥123.2 mg/mL
  10. CCG-1423
    B4897 CCG-1423
    Target: Rho
    Summary: RhoA inhibitor
      ≥21 mg/mL

Items 1-10 of 12

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