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Protein Ser/Thr Phosphatases

Protein Ser/Thr phosphatases, belonging to the superfamily of protein phosphatases, are a diverse group of phosphatases that catalyze dephosphorylation and specifically remove phosphate groups from phosphorylated Ser and Thr residues within their substrates. Protein Ser/Thr phosphatases are comprised of two distinct families of phosphatases, including PPP phosphatases and PPM (or PP2C-related) phosphatases, which are coded by two unrelated gene families but share remarkably similar architecture of catalytic domains. PPP family was initially divided into two classes, type-I phosphatases (PP1) and type-2 phosphatases (PP2) consisting of PP2A, PP2B and PP2C isoforms. Novel protein phosphatases, such as PP4, PP5, PP6 and PP7, are also included in PPP family. PPM family is comprised of a number of Mg2+-dependent phosphatases encoded by different genes, which are structurally related to PP2C.

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  1. bpV(HOpic) (potassium salt, technical grade)
    Catalog No. :
    C4614
    protein tyrosine phosphatases (PTPs) inhibitor
  2. PTP Inhibitor IV
    Catalog No. :
    C4401
    PTP inhibitor
  3. β-Glycerophosphate (sodium salt hydrate)
    Catalog No. :
    C4347
    protein phosphatase inhibitor
  4. PRL-3 Inhibitor
    Catalog No. :
    C3996
    phosphatase of regenerating liver 3 (PRL-3) inhibitor
  5. Cantharidic Acid (sodium salt)
    Catalog No. :
    C3898
    PP1 and PP2A inhibitor
  6. PTP Inhibitor I
    Catalog No. :
    C3607
    tyrosine phosphatase (PTP) inhibitor
  7. PTP Inhibitor II
    Catalog No. :
    C3591
    protein tyrosine phosphatase (PTP) inhibitor
  8. Sanguinarine chloride
    Catalog No. :
    B5970
    Inhibitor of PP2C and MKP-1
  9. Sephin1
    Catalog No. :
    A8708
    Selective PPP1R15A inhibitor
    Sephin1 is a selective inhibitor of stress-induced PPP1R15A and targets disease associated with accumulation of misfolded protein.
  10. LB-100
    Catalog No. :
    B4846
    protein phosphatase 2A(PP2A)inhibitor

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