PI3K
PI3K (phosphatidylinositol-4,5-bisphosphate 3-kinase) is a family of enzymes involved in cellular functions such as cell growth, proliferation, differentiation, motility, survival and intracellular trafficking, which in turn are involved in cancer.
- B7826 GDC-0084Summary: PI3K and mTOR inhibitor, brain-permeable
- C5012 GSK2269557Summary: inhibitor of PI3Kδ
- C4243 AS-041164Summary: PI3Kγ inhibitor
- C3103 INK1117Summary: PI3Kα inhibitor
- C3271 PX 866Summary: PI3K inhibitor
- B6178 AZD8835Summary: PI3Kα and PI3Kδ inhibitor
- B6173 GSK2292767Summary: PI3Kδ inhibitor,potent and selective
- B6099 LY3023414Target: Akt|PI3K|mTOR|DNA-PKSummary: class I PI3K isoforms, mTOR and DNA-PK inhibitor
- B6013 AMG319Summary: PI3Kδ inhibitor
- B5950 AZD8186Target: PI3KSummary: Potent and selective inhibitor of PI3Kβ and PI3Kδ