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PI3K

PI3K (phosphatidylinositol-4,5-bisphosphate 3-kinase) is a family of enzymes involved in cellular functions such as cell growth, proliferation, differentiation, motility, survival and intracellular trafficking, which in turn are involved in cancer.

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  1. GDC-0941
    A8210 GDC-0941
     10 Citation
    Target: PI3K
    Summary: PI3K inhibitor,potent and selective
      ≥25.7 mg/mL
  2. BEZ235 (NVP-BEZ235)
    A8246 BEZ235 (NVP-BEZ235)
     2 Citation
    Summary: PI3K/mTOR inhibitor,ATP-competitve
      insoluble in DMSO; insoluble in EtOH; insoluble in H2O
  3. ZSTK474
    A8248 ZSTK474
    Summary: Potent PI3K inhibitor
      insoluble in H2O; insoluble in EtOH; ≥20.85 mg/mL
  4. LY 294002
    A8250 LY 294002
     16 Citation
    Target: PI3K
    Summary: Potent PI3K inhibitor
  5. PI-103
    A2067 PI-103
     1 Citation
    Summary: Class I PI3K, mTOR and DNA-PK inhibitor
      ≥21.9 mg/mL
  6. XL147
    A5112 XL147
    Target: PI3K
    Summary: PI3K inhibitor,selective and reversible
      ≥22.45 mg/mL
  7. TGX-221
    A2681 TGX-221
    Target: PI3K
    Summary: PI3Kβ inhibitor,potent,selective and ATP competitive
      insoluble in H2O; insoluble in EtOH; ≥68.7 mg/mL
  8. Quercetin dihydrate
    A2552 Quercetin dihydrate
    Target: PI3K|PIM1 kinase|phospholipase A2
    Summary: PLA2 and PI 3-kinase inhibitor
      ≥33.8 mg/mL
  9. TG100-115
    A2754 TG100-115
    Target: PI3K
    Summary: PI3Kγ/PI3Kδ inhibitor
      insoluble in H2O; insoluble in EtOH; ≥3.46 mg/mL
  10. PIK-90
    A2764 PIK-90
    Summary: PI3K inhibitor,potent selective
      insoluble in DMSO

Items 1-10 of 62

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