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PI3K

PI3K (phosphatidylinositol-4,5-bisphosphate 3-kinase) is a family of enzymes involved in cellular functions such as cell growth, proliferation, differentiation, motility, survival and intracellular trafficking, which in turn are involved in cancer.

Relate Categories
Category
  • AMPK 17items
  • Akt 29items
  • CK2 8items
  • DNA-PK 5items
  • GSK-3 17items
  • MELK 2items
  • PDK-1 9items
  • PI3K 62items
  • PI4K 1item
  • PIKfyve 1item
  • PKB 1item
  • S6 Kinase 9items
  • eNOS 2items
  • mTOR 29items
Specificity
  1. Selective 21 items
Reversibility
  1. Reversible 2 items
Target
  1. Histone Deacetylases (HDACs) 1 item
  2. Akt 3 items
  3. PI3K 30 items
  4. mTOR 7 items
  5. Eph Receptors 1 item
  6. VEGFR 1 item
  7. PDGFR 1 item
  8. Bcr-Abl 1 item
  9. Src 1 item
  10. DNA-PK 3 items
  11. P110 1 item
  12. Hck 1 item
  13. PIM1 kinase 1 item
  14. phospholipase A2 1 item
Reported Experiments
  1. Animal Experiments 30 items
  2. Cell Experiments 26 items
Related Disease
  1. Bladder Carcinoma 1 item
  2. Breast Cancer 5 items
  3. Cancer 22 items
  4. Cholangiocarcinoma 1 item
  5. Chronic Lymphocytic Leukemia 1 item
  6. Colon Carcinoma 1 item
  7. Colorectal Cancer 1 item
  8. Glioblastoma 2 items
  9. Glioma 3 items
  10. Lung Cancer 1 item
  11. Melanoma 1 item
  12. Neuroblastoma 1 item
  13. Non-small Cell Lung Cancer 1 item
  14. Ovarian Cancer 1 item
  15. Pancreatic Cancer 3 items
  16. Prostate Cancer 1 item
  17. Rheumatoid Arthritis 1 item