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Smoothened

Smoothened is a G protein-coupled receptor of the hedgehog signaling pathway.

Items 1-10 of 11

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  1. Purmorphamine
    A8228 Purmorphamine
    Summary: Hedgehog agonist
  2. PF-04449913
    B3283 PF-04449913
    Target: Smoothened
    Summary: Antagonist of smoothened
      ≥20.15 mg/mL
  3. SMANT hydrochloride
    B5674 SMANT hydrochloride
    Summary: Smoothened (Smo) signaling inhibitor
      <7.51 mg/mL
  4. M 25
    B5766 M 25
    Summary: Smoothened (Smo) receptor antagonist
      <37.95 mg/mL
  5. GSA 10
    B5767 GSA 10
    Summary: Smoothened (Smo) receptor agonist
      soluble in DMSO
  6. ALLO-1
    C4582 ALLO-1
    Summary: SMO antagonist
      ≤20 mg/mL
  7. LDE225 (NVP-LDE225,Erismodegib)
    B2266 LDE225 (NVP-LDE225,Erismodegib)
     1 Citation
    Target: Smoothened
    Summary: Smoothened inhibitor,potent and selective
      ≥24.3 mg/mL
  8. MRT 10
    B7685 MRT 10
    Summary: Smoothened (Smo) receptor antagonist
      Soluble in DMSO
  9. BMS-833923
    A3258 BMS-833923
    Target: Smoothened
    Summary: Smoothened inhibitor
      ≥47.4 mg/mL
  10. HhAntag
    A3460 HhAntag
    Summary: GLI1-mediated transcription inhibitor
      insoluble in H2O; ≥13.3 mg/mL

Items 1-10 of 11

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