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mTOR

MTOR (mechanistic target of rapamycin) is a serine/threonine kinase that regulates cellular metabolism, growth ad survival. It mediates the cellular response to stress, growth factor and hormone etc. It is involved in cancer, aging and neurodegenerative diseases etc.

Items 1-10 of 29

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  1. Rapalink-1
    A8764 Rapalink-1
    Target: mTOR
    Summary: third-generation mTOR inhibitor
      ≥178.4 mg/mL
  2. GNE-493
    B8000 GNE-493
    Summary: Pan-PI3K/mTOR inhibitor
      Soluble in DMSO
  3. GNE-477
    B8001 GNE-477
    Summary: dual PI3K/mTOR inhibitor
      insoluble in H2O; insoluble in EtOH; ≥16.69 mg/mL
  4. MHY1485
    B5853 MHY1485
     2 Citation
    Target: mTOR
    Summary: mTOR activator, autophage inhibitor
      insoluble in EtOH; insoluble in H2O; ≥19.35 mg/mL
  5. KU-0063794
    A5078 KU-0063794
    Target: mTOR
    Summary: MTORC1 and mTORC2 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥11.65 mg/mL
  6. WYE-354
    A1266 WYE-354
    Summary: MTOR inhibitor,potent,ATP-competitive and cell-permeable
      ≥49.6 mg/mL
  7. AZD8055
    A8214 AZD8055
     2 Citation
    Target: mTOR
    Summary: MTOR inhibitor
      ≥23.3 mg/mL
  8. Torin 1
    A8312 Torin 1
     7 Citation
    Target: mTOR
    Summary: MTOR inhibitor,potent and selective
  9. Temsirolimus
    A8314 Temsirolimus
    Summary: MTOR inhibitor
      ≥51.5 mg/mL
  10. PP242
    A8318 PP242
    Target: mTOR
    Summary: MTOR inhibitor, selective and ATP-competitive

Items 1-10 of 29

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