mTOR
MTOR (mechanistic target of rapamycin) is a serine/threonine kinase that regulates cellular metabolism, growth ad survival. It mediates the cellular response to stress, growth factor and hormone etc. It is involved in cancer, aging and neurodegenerative diseases etc.
- A8764 Rapalink-1Target: mTORSummary: third-generation mTOR inhibitor
- C4204 OXA-01Summary: mTORC1 and mTORC2 inhibitor
- B6171 CC-223Summary: mTOR inhibitor, orally bioavailable
- B5853 MHY14852 CitationTarget: mTORSummary: mTOR activator, autophage inhibitor
- B8001 GNE-477Summary: dual PI3K/mTOR inhibitor
- B8000 GNE-493Summary: Pan-PI3K/mTOR inhibitor
- B1641 WAY-600Target: mTORSummary: MTOR inhibitor
- B1639 Ridaforolimus (Deforolimus, MK-8669)Target: mTORSummary: MTOR inhibitor
- B1638 WYE-687Summary: MTOR inhibitor,ATP-competitive and selective
- B2184 GDC-0980 (RG7422)Summary: Class I PI3K inhibitor for PI3Kα/β/δ/γ