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mTOR

MTOR (mechanistic target of rapamycin) is a serine/threonine kinase that regulates cellular metabolism, growth ad survival. It mediates the cellular response to stress, growth factor and hormone etc. It is involved in cancer, aging and neurodegenerative diseases etc.

Items 11-20 of 29

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  1. PP242
    A8318 PP242
    Target: mTOR
    Summary: MTOR inhibitor, selective and ATP-competitive
  2. AZD2014
    A8373 AZD2014
    Summary: Novel mTOR inhibitor
      ≥23.15 mg/mL
  3. INK 128 (MLN0128)
    A8551 INK 128 (MLN0128)
     4 Citation
    Target: mTOR
    Summary: MTOR(TORC-1/-2) inhibitor,potent and selective
      insoluble in H2O; ≥15.45 mg/mL
  4. GSK2126458
    A8556 GSK2126458
     1 Citation
    Target: PI3K|mTOR
    Summary: PI3K/mTOR inhibitor
      ≥25.3 mg/mL
  5. AKT/mTOR Set I
    A9904 AKT/mTOR Set I
    Summary: For inhibiting AKT/mTOR
  6. WYE-125132 (WYE-132)
    B1642 WYE-125132 (WYE-132)
    Target: mTOR
    Summary: ATP-competitive mTOR inhibitor, highly potent
      insoluble in EtOH; insoluble in H2O; ≥13 mg/mL
  7. OSI-027
    B1637 OSI-027
    Summary: MTORC1/ mTORC2 inhibitor
      insoluble in EtOH; insoluble in H2O; ≥32.5 mg/mL
  8. Torin 2
    B1640 Torin 2
     6 Citation
    Target: mTOR|DNA-PK|ATM/ATR
    Summary: MTOR inhibitor,highly potent and selective
      ≥21.6 mg/mL
  9. GDC-0980 (RG7422)
    B2184 GDC-0980 (RG7422)
    Summary: Class I PI3K inhibitor for PI3Kα/β/δ/γ
      ≥21.35 mg/mL
  10. GNE-493
    B8000 GNE-493
    Summary: Pan-PI3K/mTOR inhibitor
      Soluble in DMSO

Items 11-20 of 29

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