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mTOR

MTOR (mechanistic target of rapamycin) is a serine/threonine kinase that regulates cellular metabolism, growth ad survival. It mediates the cellular response to stress, growth factor and hormone etc. It is involved in cancer, aging and neurodegenerative diseases etc.

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  1. GNE-477
    B8001 GNE-477
    Summary: dual PI3K/mTOR inhibitor
      insoluble in H2O; insoluble in EtOH; ≥16.69 mg/mL
  2. MHY1485
    B5853 MHY1485
     2 Citation
    Target: mTOR
    Summary: mTOR activator, autophage inhibitor
      insoluble in EtOH; insoluble in H2O; ≥19.35 mg/mL
  3. CC-223
    B6171 CC-223
    Summary: mTOR inhibitor, orally bioavailable
      insoluble in H2O; ≥108 mg/mL
  4. OXA-01
    C4204 OXA-01
    Summary: mTORC1 and mTORC2 inhibitor
      ≤3 mg/mL
  5. WYE-687
    B1638 WYE-687
    Summary: MTOR inhibitor,ATP-competitive and selective
      insoluble in H2O; insoluble in EtOH; insoluble in DMSO
  6. Ridaforolimus (Deforolimus, MK-8669)
    B1639 Ridaforolimus (Deforolimus, MK-8669)
    Target: mTOR
    Summary: MTOR inhibitor
      ≥49.5 mg/mL
  7. WAY-600
    B1641 WAY-600
    Target: mTOR
    Summary: MTOR inhibitor
      ≥12.38 mg/mL
  8. Rapamycin (Sirolimus)
    A8167 Rapamycin (Sirolimus)
     69 Citation
    Target: mTOR
    Summary: mTOR inhibitor
      ≥45.7 mg/mL
  9. Everolimus (RAD001)
    A8169 Everolimus (RAD001)
     8 Citation
    Target: mTOR
    Summary: MTOR inhibitor
      ≥47.91 mg/mL

Items 21-29 of 29

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