mTOR
MTOR (mechanistic target of rapamycin) is a serine/threonine kinase that regulates cellular metabolism, growth ad survival. It mediates the cellular response to stress, growth factor and hormone etc. It is involved in cancer, aging and neurodegenerative diseases etc.
- B1639 Ridaforolimus (Deforolimus, MK-8669)Target: mTORSummary: MTOR inhibitor
- B1641 WAY-600Target: mTORSummary: MTOR inhibitor
- A8167 Rapamycin (Sirolimus)15 CitationTarget: mTORSummary: Original antifungal antibiotic
- A8169 Everolimus (RAD001)8 CitationTarget: mTORSummary: MTOR inhibitor
- A8764 Rapalink-1Target: mTORSummary: third-generation mTOR inhibitor
- A3568 LY 303511Summary: MTOR inhibitor
- A3637 GDC-mTOR inhibitorSummary: MTOR inhibitor
- A3664 Nordihydroguaiaretic acidSummary: Anti-tumor agent;lipoxygenase inhibitor
- A3940 XL388Summary: MTOR inhibitor,highly potent and selective