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IMPDH

IMPDH (inosine-5′-monophosphate dehydrogenase) catalyzes the initial rate-limiting step in the de novo guanine nucleotides synthesis. It is important for DNA/RNA synthesis, cell growth and malignant development etc.

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  1. Mizoribine
    Catalog No. :
    B1472
    DNA/RNA synthesis inhibitor
    Mizoribine is a immunosuppressive agents (IC50=100 uM) that inhibit the proliferation of lymphocytes selectively, via inhibition of IMPDH.

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